8-(2,3-difluoro-4-ethoxyphenyl)-1,4-dioxaspiro[4.5]decane | 220437-00-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 8-(2,3-difluoro-4-ethoxyphenyl)-1,4-dioxaspiro[4.5]decane
• 英文别名: 8-(4-ethoxy-2,3-difluorophenyl)-1,4-dioxaspiro[4.5]decane；4-(2,3-difluoro-4-ethoxyphenyl)-cyclohexanone monoethylene acetal
• CAS: 220437-00-3
• 化学式: C₁₆H₂₀F₂O₃
• 分子量: 298.33
• InChiKey: YQWHKNJWTGZNBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  8-(2,3-difluoro-4-ethoxyphenyl)-1,4-dioxaspiro[4.5]decane 在 lithium aluminium tetrahydride 、 甲酸 作用下， 以 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 9.0h， 生成 4-(4-Ethoxy-2,3-difluorophenyl)cyclohexan-1-ol
  参考文献：
  名称：

  LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION USING SAME, AND LIQUID CRYSTAL DISPLAY ELEMENT

  摘要：

  公开号：

  EP2484658B1
• 作为产物：
  描述：

  1,4-环己二酮单乙二醇缩酮 在 potassium hydrogensulfate 、 正丁基锂 、 四甲基乙二胺 、 5%-palladium/activated carbon 作用下， 以 四氢呋喃 、 正己烷 、 甲苯 为溶剂， 反应 21.5h， 生成 8-(2,3-difluoro-4-ethoxyphenyl)-1,4-dioxaspiro[4.5]decane
  参考文献：
  名称：

  液晶化合物、液晶組成物及び液晶表示素子

  摘要：

  这个问题是关于提高液晶化合物的Δn值。这个发明的一个方面是液晶化合物，其由下面的一般式（i）表示。【化1】[在式中，Ri1代表碳原子数为1〜15的烷基等，Ri2代表氟原子或碳原子数为1〜15的烷基等，Ai1和Ai2代表1,4-环己烯基等，Zi1和Zi2代表单键，-CH2CH2-等，ni1代表1〜4的整数，mi1代表0〜3的整数，并且ni1+mi1为1〜4。][选择图]无

  公开号：

  JP2020011937A

文献信息

• LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：KOBAYASHI Masahide

  公开号：US20120193577A1

  公开（公告）日：2012-08-02

  The invention provides a liquid crystal compound having a high stability to heat, light or the like, a wide temperature range of a nematic phase, a small viscosity, a suitable optical anisotropy, a large elastic constant K 33 , a large negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds. The invention provides a liquid crystal composition having characteristics similar to these of the compound. The invention provides a liquid crystal display device having a short response time, low electric power consumption, a low driving voltage, a large contrast and a wide temperature range in which the device can be used. The compound is a 2,3-difluorobenzene derivative (1) having a combination of a cyclohexane ring, a cyclohexene ring or a benzene ring phenyl and a butene bonding group. The liquid crystal composition includes this compound, and the liquid crystal display device contains this composition.

  该发明提供了一种液晶化合物，具有高热稳定性、耐光性等特点，具有宽的向列相温度范围，低粘度，适当的光学各向异性，大的弹性常数K33，大的负介电各向异性，并且与其他液晶化合物具有良好的兼容性。该发明提供了一种具有与该化合物相似特性的液晶组合物。该发明提供了一种具有短响应时间、低电功耗、低驱动电压、大对比度和可以使用的宽温度范围的液晶显示装置。该化合物是一种2,3-二氟苯衍生物(1)，具有环己烷环、环己烯环或苯环苯基和丁烯键合基的组合。该液晶组合物包括这种化合物，液晶显示装置包含该组合物。
• Alkenyl compound having a negative delta epsilon value, liquid crystal composition, and liquid crystal display device
  申请人：CHISSO CORPORATION

  公开号：US20040065866A1

  公开（公告）日：2004-04-08

  There are provided a liquid crystalline compound having a large negative &Dgr;&egr;, low viscosity, a large K 33 /K 11 value, a small &Dgr;&egr;/&egr;L and mutually excellent solubility even at extremely low temperature; a liquid crystal composition prepared from a liquid crystalline compound; and a liquid crystal display device fabricated from such a liquid crystal composition. The liquid crystalline compound of the present invention is a liquid crystalline compound represented by the following general formula (1): 1 where, R 1 represents hydrogen, fluorine, an alkyl group having 1 to 15 carbon atoms, or an alkenyl group having 2 to 15 carbon atoms; each of rings A 1 , A 2 , and A 3 independently represents trans-1,4-cyclohexylene group, 1,4-cyclohexenylene group, trans-1,4-silacyclohexylene group, 1,4-phenylenegroup, 2,3-difluoro-1,4-phenylene group, 2-fluoro-1,4-phenylene group, 3-fluoro-1,4-phenylene group, pyrimidine-2,5-diyl group, pyridine-2,5-diyl group, 1,3-dioxane-2,5-diyl group, tetrahydropyrane-2,5-diyl group, 1,3-dithiane-2,5-diyl group, or tetrahydrothiopyrane-2,5-diyl group; X 1 represents hydrogen or fluorine; Y 1 represents hydrogen or an alkyl group having 1 to 15 carbon atoms; 1 represents an integer from 1 to 10; and each of m and n independently represents 0 or 1.

  本发明提供了一种具有较大负的&Dgr;&egr;、低粘度、大的K33/K11值、小的&Dgr;&egr;/&egr;L以及即使在极低温度下也具有相互良好的溶解性的液晶化合物；由液晶化合物制备的液晶组合物；以及由这种液晶组合物制造的液晶显示装置。本发明的液晶化合物是由下列通式(1)表示的液晶化合物：1 其中，R1表示氢、氟、具有1至15个碳原子的烷基或具有2至15个碳原子的烯基；每个环A1、A2和A3独立地表示反-1,4-环己基、1,4-环己烯基、反-1,4-硅杂环己基、1,4-苯基、2,3-二氟-1,4-苯基、2-氟-1,4-苯基、3-氟-1,4-苯基、嘧啶-2,5-二基基团、吡啶-2,5-二基基团、1,3-二噁烷-2,5-二基基团、四氢吡喃-2,5-二基基团、1,3-二硫杂环己烷-2,5-二基基团或四氢硫杂环己烷-2,5-二基基团；X1表示氢或氟；Y1表示氢或具有1至15个碳原子的烷基；1表示1至10的整数；m和n各自独立地表示0或1。
• Alkenyl compound having a negative &Dgr;&egr; value, liquid crystal composition, and liquid crystal display device
  申请人：Chisso Corporation

  公开号：US06692657B1

  公开（公告）日：2004-02-17

  Liquid crystalline compounds having a large negative &Dgr;∈ low viscosity, a large K33/K11 value, a small &Dgr;∈/&Dgr;⊥ and mutually excellent solubility even at low temperature, compositions containing at least one of the compounds and liquid crystal display devices containing such a liquid crystal compositions are disclosed.

  本发明涉及一种具有大负Δ∈、低粘度、大K33/K11值、小Δ∈/Δ⊥值以及即使在低温下也具有相互优异的溶解性的液晶化合物，含有该化合物之一的组合物以及包含该液晶组合物的液晶显示器装置。
• LIQUID CRYSTAL COMPOUND HAVING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME
  申请人：Yamashita Junichi

  公开号：US20120190897A1

  公开（公告）日：2012-07-26

  The invention provides a liquid crystal compound having general physical properties necessary for the liquid crystal compound, namely, stability to heat, light and so forth, a small viscosity, a refractive index anisotropy having a suitable magnitude value, a dielectric anisotropy having a suitable magnitude value, steep electrooptical characteristics, a wide temperature range of a nematic phase, and an excellent compatibility with other liquid crystal compounds, in particular, a liquid crystal compound having a wide temperature range of the nematic phase; a compound represented by formula (i): wherein, for example, R 1 and R 2 are alkyl having 1 to 8 carbons or alkenyl having 2 to 8 carbons; ring A 1 is trans-1,4-cyclohexylene or 1,4-phenylene; ring A 2 is trans-1,4-cyclohexylene or 2,3-difluoro-1,4-phenylene; Q 1 and Q 2 are fluorine or chlorine; and h is 0, 1 or 2.

  本发明提供了一种液晶化合物，具有液晶化合物所需的一般物理性能，即耐热、耐光等稳定性，小粘度，适当大小的折射率各向异性，适当大小的介电各向异性，陡峭的电光特性，宽的向列相温度范围，以及与其他液晶化合物的优异相容性，特别是一种具有宽的向列相温度范围的液晶化合物；其中，化合物的结构式为（i）：其中，例如，R1和R2是具有1至8个碳或2至8个碳的烷基或烯基；环A1是反-1,4-环己基或1,4-苯基；环A2是反-1,4-环己基或2,3-二氟-1,4-苯基；Q1和Q2是氟或氯；h为0、1或2。
• Liquid crystal compound, liquid crystal composition and liquid crystal display device
  申请人：Kobayashi Masahide

  公开号：US08580146B2

  公开（公告）日：2013-11-12

  A liquid crystal compound having a high stability to heat, light or the like, a wide temperature range of a nematic phase, a small viscosity, a suitable optical anisotropy, a large elastic constant K33, a large negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds. Also, a liquid crystal composition having characteristics similar to these of the compound. Additionally, a liquid crystal display device having a short response time, low electric power consumption, a low driving voltage, a large contrast and a wide temperature range in which the device can be used. The compound is a 2,3-difluorobenzene derivative (1) having a combination of a cyclohexane ring, a cyclohexene ring or a benzene ring phenyl and a butene bonding group. The liquid crystal composition includes this compound, and the liquid crystal display device contains this composition.

  该液晶化合物具有高热稳定性、光稳定性、宽的向列相温度范围、低粘度、适当的光学各向异性、大的弹性常数K33、大的负介电各向异性以及与其他液晶化合物的良好相容性。此外，液晶组合物具有类似于该化合物的特性。此外，液晶显示器具有短响应时间、低电功耗、低驱动电压、大对比度以及可以使用的宽温度范围。该化合物是一种2,3-二氟苯衍生物（1），具有一个环己烷环、一个环己烯环或苯环苯基和一个丁烯键结合基的组合。该液晶组合物包括此化合物，并且液晶显示器包含此组合物。