2,2,3,3,3-Pentafluoro-1-(2,2,3,3,3-pentafluoropropoxy)propan-1-ol | 648430-14-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 英文名称: 2,2,3,3,3-Pentafluoro-1-(2,2,3,3,3-pentafluoropropoxy)propan-1-ol
• 英文别名: 2,2,3,3,3-pentafluoro-1-(2,2,3,3,3-pentafluoropropoxy)propan-1-ol
• CAS: 648430-14-2
• 化学式: C₆H₄F₁₀O₂
• 分子量: 298.081
• InChiKey: AKTSSHIHCGBGGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  六氟丙烯 、 2,2,3,3,3-Pentafluoro-1-(2,2,3,3,3-pentafluoropropoxy)propan-1-ol 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 生成 C2F5CH(Och2C2F5)ocf2cfhcf3
  参考文献：
  名称：

  ヒドロフルオロアセタール化合物及びその製造法と利用

  摘要：

  要解决的问题：提供一种新颖的氢氟乙醛化合物。解决方案：提供一种根据公式[I]的化合物R[CH(-O-CHR)(-O-CF-CFH-R)]，其中n为1或2，m为1、2或3，R是可选的取代基，并选自高度氟化的直链、支链、环状或其组合的烷基基团，当n为1时，可能包含一个或多个链上结合的杂原子；R是可选的取代基，并选自高度氟化的直链、支链、环状或其组合的亚烷基基团，当n为2时，可能包含一个或多个链上结合的杂原子；每个R独立地是可选的取代基，并选自直链、支链、环状或其组合的烷基基团，可能包含一个或多个链上结合的杂原子；至少一个R是高度氟化的；每个R选自氟和高度氟化的直链、支链、环状或其组合的烷基基团，可能包含一个或多个链上结合的杂原子。

  公开号：

  JP2015044851A

文献信息

• HYDROFLUOROACETAL COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE
  申请人：Flynn Richard M.

  公开号：US20090326083A1

  公开（公告）日：2009-12-31

  The present disclosure provides a compound according to the formula: R f 1 [CH(—O—CH (3-m) R f 2 m )(—O—CF 2 —CFH—R f 3 )] n [I] wherein n is 1 or 2, wherein m is 1, 2 or 3, wherein, when n is 1, R f 1 is selected from the group consisting of highly fluorinated alkyl groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms; wherein, when n is 2, R f 1 is selected from the group consisting of highly fluorinated alkylene groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms; wherein each R f 2 is independently selected from the group consisting of alkyl groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms; wherein at least one R f 2 is highly fluorinated; wherein each R f 3 is independently selected from the group consisting of fluorine and highly fluorinated alkyl groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms. Also provided are methods of use and manufacture of such compounds.

  本公开提供了一种按照式子Rf1[CH(—O—CH(3-m)Rf2m)(—O—CF2—CFH—Rf3)]n[I]的化合物，其中n为1或2，m为1、2或3，当n为1时，Rf1选自高度氟化的线性、支链、环状或其组合的烷基基团，可以选择性地被取代，并且可以选择性地包含一个或多个链合杂原子；当n为2时，Rf1选自高度氟化的线性、支链、环状或其组合的烷基烷基团，可以选择性地被取代，并且可以选择性地包含一个或多个链合杂原子；每个Rf2独立地选自线性、支链、环状或其组合的烷基基团，可以选择性地被取代，并且可以选择性地包含一个或多个链合杂原子；至少一个Rf2高度氟化；每个Rf3独立地选自氟和高度氟化的线性、支链、环状或其组合的烷基基团，可以选择性地被取代，并且可以选择性地包含一个或多个链合杂原子。还提供了这种化合物的使用和制造方法。
• Hydrofluoroacetal compounds and processes for their preparation and use
  申请人：3M Innovative Properties Company

  公开号：US08071816B2

  公开（公告）日：2011-12-06

  The present disclosure provides a compound according to the formula: Rf1[CH(—O—CH(3-m)Rf2m)(—O—CF2—CFH—Rf3)]n   [I] wherein n is 1 or 2, wherein m is 1, 2 or 3, wherein, when n is 1, Rf1 is selected from the group consisting of highly fluorinated alkyl groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms; wherein, when n is 2, Rf1 is selected from the group consisting of highly fluorinated alkylene groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms; wherein each Rf2 is independently selected from the group consisting of alkyl groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms; wherein at least one Rf2 is highly fluorinated; wherein each Rf3 is independently selected from the group consisting of fluorine and highly fluorinated alkyl groups which are linear, branched, cyclic, or a combination thereof, which may optionally be substituted, and which may optionally contain one or more catenated heteroatoms. Also provided are methods of use and manufacture of such compounds.

  本公开提供了一种化合物，其化学式为：Rf1 [CH（—O—CH（3-m）Rf2m）（—O—CF2—CFH—Rf3）]n [I]，其中n为1或2，m为1、2或3，当n为1时，Rf1选自高度氟化的直链、支链、环状或其组合的烷基基团，可选地取代，并可选地含有一个或多个串联的杂原子；当n为2时，Rf1选自高度氟化的直链、支链、环状或其组合的烷基烷基团，可选地取代，并可选地含有一个或多个串联的杂原子；每个Rf2独立地选自线性、支链、环状或其组合的烷基基团，可选地取代，并可选地含有一个或多个串联的杂原子；至少一个Rf2是高度氟化的；每个Rf3独立地选自氟和高度氟化的直链、支链、环状或其组合的烷基基团，可选地取代，并可选地含有一个或多个串联的杂原子。还提供了使用和制造这种化合物的方法。
• ヒドロフルオロアセタール化合物及びその製造法と利用
  申请人：3M创新有限公司

  公开号：JP2015044851A

  公开（公告）日：2015-03-12

  PROBLEM TO BE SOLVED: To provide a novel hydrofluoroacetal compound.SOLUTION: There is provided a compound according to the formula [I] of R[CH(-O-CHR)(-O-CF-CFH-R)], where n is 1 or 2, m is 1, 2 or 3, Ris optionally substituted and selected from the group consisting of highly fluorinated alkyl groups which are linear, branched, cyclic or combination thereof, which may optionally contain a hetero atom bound to one or more chain when n is 1; Ris optionally substituted and selected from the group consisting of highly fluorinated alkylene groups which are linear, branched, cyclic or combination thereof, which may optionally contain a hetero atom bound to one or more chain when n is 2; each Ris independently optionally substituted and selected from the group consisting of alkyl groups which are linear, branched, cyclic or combination thereof, which may optionally contain a hetero atom bound to one or more chain; at least one of Ris highly fluorinated; and each Ris selected from the group consisting of fluorine and a highly fluorinated alkyl groups which are linear, branched, cyclic or combination thereof, which may optionally contain a hetero atom bound to one or more chain.

  要解决的问题：提供一种新颖的氢氟乙醛化合物。解决方案：提供一种根据公式[I]的化合物R[CH(-O-CHR)(-O-CF-CFH-R)]，其中n为1或2，m为1、2或3，R是可选的取代基，并选自高度氟化的直链、支链、环状或其组合的烷基基团，当n为1时，可能包含一个或多个链上结合的杂原子；R是可选的取代基，并选自高度氟化的直链、支链、环状或其组合的亚烷基基团，当n为2时，可能包含一个或多个链上结合的杂原子；每个R独立地是可选的取代基，并选自直链、支链、环状或其组合的烷基基团，可能包含一个或多个链上结合的杂原子；至少一个R是高度氟化的；每个R选自氟和高度氟化的直链、支链、环状或其组合的烷基基团，可能包含一个或多个链上结合的杂原子。