7-t-butylhept-2,4,6-trien-1-al | 147283-03-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 7-t-butylhept-2,4,6-trien-1-al
• 英文别名: 8,8-Dimethylnona-2,4,6-trienal；8,8-dimethylnona-2,4,6-trienal
• CAS: 147283-03-2
• 化学式: C₁₁H₁₆O
• 分子量: 164.247
• InChiKey: XNTAETHVVARLSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2,4-己二烯醛 在 sodium hydroxide 、 sodium perchlorate 、 三氯氧磷 作用下， 以 四氢呋喃 为溶剂， 反应 7.0h， 生成 7-t-butylhept-2,4,6-trien-1-al
  参考文献：
  名称：

  A convenient synthetic entry into aldehydes with extended conjugation

  摘要：

  Variable-length donor-acceptor polyenes 1-18 were synthesized. In the key step, a polyenal was appended to an aromatic donor through nucleophilic attack oi an organolithium reagent on a vinylogous amide. Yields of aldehydes and dialdehydes in the one-pot process ranged from 12-64% and depended upon number of repeat units (n=1-3) in the polyene chain. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00047-1

文献信息

• A convenient synthetic entry into aldehydes with extended conjugation
  作者：Andrienne C. Friedli、Edward Yang、Seth R. Marder

  DOI：10.1016/s0040-4020(97)00047-1

  日期：1997.2

  Variable-length donor-acceptor polyenes 1-18 were synthesized. In the key step, a polyenal was appended to an aromatic donor through nucleophilic attack oi an organolithium reagent on a vinylogous amide. Yields of aldehydes and dialdehydes in the one-pot process ranged from 12-64% and depended upon number of repeat units (n=1-3) in the polyene chain. (C) 1997 Elsevier Science Ltd.