pentaethylene glycol dithiol | 89141-20-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: pentaethylene glycol dithiol
• 英文别名: 3,6,9,12-Tetraoxatetradecane-1,14-dithiol；2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethanethiol
• CAS: 89141-20-8
• 化学式: C₁₀H₂₂O₄S₂
• 分子量: 270.414
• InChiKey: JYOUFUGWIRAUMM-UHFFFAOYSA-N

物化性质

• 沸点：
  137-138 °C(Press: 0.1 Torr)
• 密度：
  1.094±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  16
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38.9
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  pentaethylene glycol dithiol 在 氧气 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 120.0h， 生成
  参考文献：
  名称：

  Efficient Synthesis of 'Redox-Switched' Naphthoquinone Thiol-Crown Ethers and Their Biological Activity Evaluation

  摘要：

  Series of naphthoquinone thiol-crown ethers had been prepared. The antibacterial, antifungal, and cytotoxic activities of these synthetic naphthoquinone thiol-crown ethers were investigated. All of the compounds tested displayed antibacterial, cytotoxic and antifungal activities. The bis-naphthoquinone thiol-crown ether 7a was the most potent inhibitor among tested analogues against Staphylococcus aureus methicillin resistance with MIC value of 2.68 muM. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0968-0896(02)00004-4
• 作为产物：
  描述：

  羟丙基淀粉磷酸酯 在 吡啶 、 三溴化磷 作用下， 以 乙醇 为溶剂， 反应 21.0h， 生成 pentaethylene glycol dithiol
  参考文献：
  名称：

  Bradshaw, Jerald S.; Krakowiak, Krzysztof E.; Izatt, Reed M., Journal of Heterocyclic Chemistry, 1990, vol. 27, # 4, p. 347 - 349

  摘要：

  DOI：

文献信息

• [EN] COMPOUNDS FOR PROVIDING A LONG-LASTING FLORAL AND FRUITY ODOR<br/>[FR] COMPOSÉS DESTINÉS À FOURNIR UNE ODEUR FLORALE ET FRUITÉE DE LONGUE DURÉE
  申请人：FIRMENICH & CIE

  公开号：WO2021122997A1

  公开（公告）日：2021-06-24

  The present invention relates to the field of perfumery. The present invention relates to compounds of formula (I) that are able to provide a long-lasting or substantive odor, in particular floral and/or fruity odor, to the environment. Moreover, the present invention relates to a method of imparting a long-lasting odor, in particular a fresh green, floral and/or fruity odor, to surfaces, such as hard surfaces, fabric, skin or hair. Furthermore, the present invention relates to the use of said compounds in perfumery, as well as the perfuming compositions or perfumed articles comprising the invention's compounds.

  本发明涉及香精领域。本发明涉及具有式(I)的化合物，能够赋予环境持久或实质性的气味，特别是花香和/或果香气味。此外，本发明涉及一种方法，能够赋予表面持久的气味，特别是清新的绿色、花香和/或果香气味，例如硬表面、织物、皮肤或头发。此外，本发明涉及在香精中使用所述化合物，以及包含本发明化合物的香水配方或香气产品。
• 신규한 화합물 및 이의 용도
  申请人：KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 한국화학연구원(319980077651)

  公开号：KR101840335B1

  公开（公告）日：2018-03-20

  본 발명은 하기 화학식 1로 표시되는 티올 화합물을 제공한다. [화학식 1] [화학식 1에서, X는 각각 독립적으로 S 또는 NR이고, R은 수소 또는 C1 내지 C7의 알킬이고, n은 각각 독립적으로 1 내지 12의 정수이고, Y는 직접결합 또는 C1 내지 C7의 알킬렌기이다.]

  本发明提供了一种被表示为化学式1的硫醇化合物。[化学式1] [在化学式1中，X分别独立地是S或NR，R是氢或C1到C7的烷基，n分别独立地是1到12的整数，Y是直链或C1到C7的亚烷基基。]
• Synthesis and Mercurophilic Properties of Sulfur-Containing Troponoid Crown Ethers
  作者：Hitoshi Takeshita、Bing Zhu Yin、Kanji Kubo、Akira Mori

  DOI：10.1246/bcsj.66.3451

  日期：1993.11

  Condensation of 2,7-dibromotropone and 7-bromo-4-isopropyl-2-(4-tolysulfonyloxy)tropone with oligoethylene glycol bis(2-mercaptoethyl) ethers gave sulfur-containing crown ether derivatives. Among these mercurophilic derivatives, triethylene glycol bis(2-mercaptoethyl) derivatives transport and extract mercury ion excellently.

  2,7-二溴托品和 7-溴-4-异丙基-2-（4-甲苯磺酰氧基）托品与低聚乙二醇双（2-巯基乙烷）醚缩合后得到含硫冠醚衍生物。在这些亲汞衍生物中，三乙二醇双（2-巯基乙基）衍生物能很好地传输和萃取汞离子。
• Synthesis and reversible mercury salt-capturing ability of troponoid-annexed dithio crown ethers
  作者：Hitoshi Takeshita、Akira Mori、Shun-ichi Hirayama

  DOI：10.1039/c39890000564

  日期：——

  Condensation of 4,6-bis(chloromethyl)-2,5-dimethoxytropone with di- and tri-ethylene glycol bis(2-mercaptoethyl) ethers gave dithio-crown ethers, which selectively included Hg2+ from aqueous solutions; the Hg2+ included was quantitatively liberated by acidification with dilute HCl, thus achieving an effective transportation of Hg2+.

  将4，6-双（氯甲基）-2，5-二甲氧肌酮与二和三乙二醇双（2-巯基乙基）醚缩合，制得二硫代冠醚，其从水溶液中选择性地包含Hg 2+。通过用稀盐酸酸化可定量释放所含的Hg 2+，从而实现Hg 2+的有效传输。
• Synthesis and Mercurophilic Properties of 2,2′-Oxybis(ethylenethio)ditropone and<i>α</i>-[2-(2-Troponylthio)ethyl]-<i>ω</i>-(2-troponylthio)oligo(oxyethylene)
  作者：Kanji Kubo、Akira Mori、Hitoshi Takeshita

  DOI：10.1246/bcsj.70.231

  日期：1997.1

  The condensation reactions of 2-(p-tolylsulfonyloxy)tropone with 2,2′-oxydiethanethiol and its α-(2-sulfanylethyl)-ω-sulfanyloligo(oxyethylene) derivatives afforded 2,2′-oxybis(ethylenethio)ditropone and α-[2-(2-troponylthio)ethyl]-ω-(2-troponylthio)oligo(oxyethylene). Reflecting the acyclic nature of the polyethylene glycol moiety, they formed the complexes with various metal ions. Among them, mercury(II)

  2-（对甲苯磺酰氧基）托酮与 2,2'-氧二乙硫醇及其 α-（2-硫烷基乙基）-ω-硫烷基低聚（氧乙烯）衍生物的缩合反应得到 2,2'-氧双（乙硫基）双托酮和 α- [2-(2-troponylthio)ethyl]-ω-(2-troponylthio)oligo(oxyethylene)。反映了聚乙二醇部分的无环性质，它们与各种金属离子形成了络合物。其中，至少在所使用的条件下，汞 (II) 盐只能通过液膜传输。