2,6-difluoro-N1-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-yl)benzene-1,3-diamine | 1380228-73-8
中文名称
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中文别名
——
英文名称
2,6-difluoro-N1-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-yl)benzene-1,3-diamine
英文别名
2,6-difluoro-N-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-yl)benzene-1,3-diamine；2,4-difluoro-3-N-[3-[9-(oxan-2-yl)purin-6-yl]pyridin-2-yl]benzene-1,3-diamine
CAS
1380228-73-8
化学式
C21H19F2N7O
mdl
——
分子量
423.425
InChiKey
YYNIDVJYKMDXQT-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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沸点：601.4±65.0 °C(Predicted)
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密度：1.56±0.1 g/cm3(Predicted)
计算性质
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辛醇/水分配系数(LogP)：2.8
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重原子数：31
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可旋转键数：4
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环数：5.0
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sp3杂化的碳原子比例：0.24
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拓扑面积：104
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氢给体数：2
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氢受体数：9
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— 6-(2-fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 1093101-52-0 C15H14FN5O 299.307 6-氯-9-(四氢-2-吡喃基)嘌呤 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 7306-68-5 C10H11ClN4O 238.677 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)propane-1-sulfonamide 1380228-80-7 C24H25F2N7O3S 529.57 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)9H-purin-6-yl)pyridin-2-ylamino)phenyl)cyclopropansulfonamide 1380228-96-5 C24H23F2N7O3S 527.555 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)9H-purin-6-yl)pyridin-2-ylamino)phenyl)cyclohexanesulfonamide 1380228-88-5 C27H29F2N7O3S 569.635 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)benzenesulfonamide 1380229-14-0 C27H23F2N7O3S 563.588 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)furan-3-sulfonamide 1380228-95-4 C25H21F2N7O4S 553.549 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)morpholine-4-sulfonamide 1380228-98-7 C25H26F2N8O4S 572.595 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)thiophene-3-sulfonamide 1380228-94-3 C25H21F2N7O3S2 569.616 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-1-methyl-1H-pyrazole-4-sulfonamide 1380229-22-0 C25H23F2N9O3S 567.579 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)pyridin-3-sulfonamide 1380229-09-3 C26H22F2N8O3S 564.575 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-4-(trifluoromethyl)benzenesulfonamide 1380228-76-1 C28H22F5N7O3S 631.586 —— 3-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)benzenesulfonamide 1380229-12-8 C27H22ClF2N7O3S 598.033 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-4-(trifluoromethoxy)benzenesulfonamide 1380228-89-6 C28H22F5N7O4S 647.585 —— 2-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)benzenesulfonamide 1380229-11-7 C27H22ClF2N7O3S 598.033 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)furan-2-sulfonamide 1380228-92-1 C25H21F2N7O4S 553.549 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)thiophene-2-sulfonamide 1380228-78-3 C25H21F2N7O3S2 569.616 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-3-(trifluoromethyl)benzenesulfonamide 1380228-74-9 C28H22F5N7O3S 631.586 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-2-methylbenzenesulfonamide 1380229-10-6 C28H25F2N7O3S 577.614 —— 3,4-dichloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)benzenesulfonamide 1380228-81-8 C27H21Cl2F2N7O3S 632.478 —— 3-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-4-fluorobenzenesulfonamide 1380229-07-1 C27H21ClF3N7O3S 616.023 —— 4-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-2-fluorobenzenesulfonamide 1380228-84-1 C27H21ClF3N7O3S 616.023 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-5-methylfuran-2-sulfonamide 1380229-02-6 C26H23F2N7O4S 567.576 —— 5-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)thiophene-2-sulfonamide 1380229-23-1 C25H20ClF2N7O3S2 604.061 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-3,4-dimethoxybenzenesulfonamide 1380228-87-4 C29H27F2N7O5S 623.64 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-1-methyl-1H-indole-5-sulfonamide 1380229-19-5 C30H26F2N8O3S 616.651 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-2,5-dimethylfuran-3-sulfonamide 1380229-04-8 C27H25F2N7O4S 581.603 —— 3-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-2-fluorobenzenesulfonamide 1380229-08-2 C27H21ClF3N7O3S 616.023 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-1-(2-nitrophenyl)methansulfonamide 1380228-86-3 C28H24F2N8O5S 622.612 —— N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)benzofuran-7-sulfonamide 1380229-16-2 C29H23F2N7O4S 603.609 —— 3-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-2-methylbenzenesulfonamide 1380228-91-0 C28H24ClF2N7O3S 612.059