2,3,4,5-tetrapropyl-cyclopenta-2,4-dienone | 105430-58-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,4,5-tetrapropyl-cyclopenta-2,4-dienone
• 英文别名: 2,3,4,5-tetrapropylcyclopentadienone；tetrapropylcyclopentadienone；cyclopentadienone；2,4-Cyclopentadien-1-one, 2,3,4,5-tetrapropyl-；2,3,4,5-tetrapropylcyclopenta-2,4-dien-1-one
• CAS: 105430-58-8
• 化学式: C₁₇H₂₈O
• 分子量: 248.409
• InChiKey: UREAXPPWHXVKLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  以 甲苯 为溶剂， 以100%的产率得到2,3,4,5-tetrapropyl-cyclopenta-2,4-dienone
  参考文献：
  名称：

  CuCl-mediated tandem CO insertion and annulation of 1,4-dilithio-1,3-dienes: formation of multiply substituted cyclopentadienones and/or their head-to-head dimers

  摘要：

  在氯化铜的介导下，1,4-二硫-1,3-二烯与一氧化碳（CO）反应，通过串联 CO 插入和有机铜化合物的分子内/分子间环加成，生成多取代环戊二烯酮和/或其头对头二聚体。

  DOI：

  10.1039/b719007g

文献信息

• Reactions of Substituted (1,3-Butadiene-1,4-diyl)magnesium, 1,4-Bis(bromomagnesio)butadienes and 1,4-Dilithiobutadienes with Ketones, Aldehydes and PhNO To Yield Cyclopentadiene Derivatives and N-Ph Pyrroles by Cyclodialkenylation
  作者：Hongyun Fang、Guotao Li、Guoliang Mao、Zhenfeng Xi

  DOI：10.1002/chem.200400025

  日期：2004.7.19

  4-Dilithiobutadiene derivatives 1, 1,4-bis(bromomagnesio)butadiene derivatives 2 and metallacyclic (1,3-butadiene-1,4-diyl)magnesium reagents 3 were prepared and their reactions with ketones, aldehydes, and PhNO were investigated. Multiply substituted cyclopentadienes and N-Ph pyrroles were formed by unprecedented reaction conditions. The carbonyl group of aldehydes and ketones was deoxygenated during

  制备了1,4-二硫代丁二烯衍生物1，1,4-双（溴镁）丁二烯衍生物2和金属环（1,3-丁二烯-1,4-二基）镁试剂3，并与酮，醛和PhNO进行了反应调查。多重取代的环戊二烯和N-Ph吡咯是通过空前的反应条件形成的。醛和酮的羰基在​​反应过程中被脱氧，并在形式上表现为一碳单元；裂解PhNO的N ＝＝ O部分，得到N-Ph吡咯衍生物。此外，揭示了这三种类型的试剂1、2和3之间的不同反应性。1,4-二锂试剂1容易与醛和酮反应；1,4-二镁试剂2与醛反应，但不与酮反应；
• Nickel(O)-mediated hydrocyanation and carbonylation reactions of alkynes with trimethylsilyl(iso)cyanide
  作者：John J. Eisch、Allen A. Aradi、Kyoung I. Han

  DOI：10.1016/s0040-4039(00)81847-x

  日期：1983.1

  Under nickel(0) mediation, trimethylsilyl(iso)cyanide serves as both as useful -hydrocyanating agent and a carbohylating agent for alkynes.

  在镍（0）的介导下，三甲基甲硅烷基（异）氰化物既可用作有用的氢氰化剂，也可用作炔烃的碳氢化剂。
• 1,1-Cycloaddition of Oxalyl Dichloride with Dialkenylmetal Compounds:  Formation of Cyclopentadienone Derivatives by the Reaction of 1,4,-Dilithio-1,3-dienes or Zirconacyclopentadienes with Oxalyl Chloride in the Presence of CuCl
  作者：Chao Chen、Chanjuan Xi、Yanfeng Jiang、Xiaoyin Hong

  DOI：10.1021/ja0506713

  日期：2005.6.1

  1,4-Dilithio-1,3-dienes or zirconacyclopentadienes reacted with oxalyl chloride in the presence of CuCl in a 1,1-cycloaddition manner to give cyclopentadienone derivatives in high yields along with the elimination of CO.
• Garlaschelli, Luigi; Malatesta, Maria Carlotta; Panzeri, Silvia, Organometallics, 1987, vol. 6, # 1, p. 63 - 72
  作者：Garlaschelli, Luigi、Malatesta, Maria Carlotta、Panzeri, Silvia、Albinati, Alberto、Ganazzoli, Fabio

  DOI：——

  日期：——
• Efficient Synthesis of Cyclopentadienone Derivatives by the Reaction of Carbon Dioxide with 1,4-Dilithio-1,3-dienes
  作者：Zhenfeng Xi、Qiuling Song

  DOI：10.1021/jo005641r

  日期：2000.12.1

  One-pot reaction of carbon dioxide with 1,4-dilithio-1,3-diene derivatives afforded cyclopentadienone derivatives bearing various substituents in high yields within several minutes.