5-Ethylphenanthridin-5-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 5-Ethylphenanthridin-5-ium
• 化学式: C15H14N+
• 分子量: 208.28
• InChiKey: KZVOVZJPHXGNRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS
  申请人：University Court of The University of Glasgow

  公开号：EP1692130A2

  公开（公告）日：2006-08-23
• [EN] PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS<br/>[FR] COMPOSES AROMATIQUES HETEROCYCLIQUES
  申请人：UNIV GLASGOW

  公开号：WO2005054241A2

  公开（公告）日：2005-06-16

  New classes of heterocyclic aromatic cationic compounds are disclosed, and in particular new classes of phenanthridinium derivatives, most notably dihydro-imidazo-phenanthridinium (DIP) compounds. These findings are based on the reaction of the middle b ring of a phenanthridinium core with primary amines to form DIP compounds (Formula A) or secondary amines to form 2-aminoalkyl phenanthridinium derivatives (Formula B). These reactions can also be applied to other classes of starting compounds which comprise a 6-membered ring aromatic heterocycle having a ring nitrogen and at least one alpha hydrogen atom which can be reacted with a primary or secondary amine.