methyl 2,3,6-tri-O-methyl α,β-D-galactopyranoside | 95340-31-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 2,3,6-tri-O-methyl α,β-D-galactopyranoside
• 英文别名: Methyl-2,3,6-tri-O-methyl-D-galactosid；(2R,3S,4S,5R)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-ol
• CAS: 95340-31-1
• 化学式: C₁₀H₂₀O₆
• 分子量: 236.265
• InChiKey: WMAJFVGSEYZPMZ-CYNREMDZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  66.38
• 氢给体数：
  1.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  (2S,3R,4S,5R)-2-[(2S,3R,4R,5R,6R)-2-[(2S,3R,4S,5R,6R)-2-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(1R,2S,4S,5'R,6R,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-yl]oxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxyoxane-3,4,5-triol 生成 methyl 2,3,6-tri-O-methyl α,β-D-galactopyranoside
  参考文献：
  名称：

  NAKANO, KIMIKO;MATSUDA, EMI;TSURUMI, KAORI;YAMASAKI, TOKUSHI;MURAKAMI, KO+, PHYTOCHEMISTRY, 27,(1988) N 10, C. 3235-3239

  摘要：

  DOI：

文献信息

• Studies on the constituents of Solanum plants. V. The constituents of S. lyratum Thunb. II.
  作者：KOTARO MURAKAMI、HISATAKA EZIMA、YOSHIHISA TAKAISHI、YOSHIO TAKEDA、TETSURO FUJITA、AKIHIKO SATO、YOKO NAGAYAMA、TOSHIHIRO NOHARA

  DOI：10.1248/cpb.33.67

  日期：——

  Two new steroidal alkaloid glycosides, tentatively named SL-c (1) and SL-d (2), were obtained from the stems of Solanum lyratum THUNB. The chemical structures of 1 and 2 were characterized respectively as β-lycotrioside and β-lycotetraoside, both having a mixture of (25ζ)-solanidan-3β, 23β-diol and (25ζ)-Δ5-solaniden-3β, 23β-diol as the aglycone moiety. These compounds markedly inhibited the growth of a human cervical cancer cell line, JTC-26.

  从Solanum lyratum THUNB的茎中获得了两种新的甾体生物碱苷，暂命名为SL-c (1)和SL-d (2)。 1和2的化学结构分别为β-lycotrioside和β-lycotetraoside，均具有(25ζ)-solaniden-3β, 23β-diol和(25ζ)-Δ5-solaniden-3β, 23β-diol的混合物：糖苷配基部分。这些化合物显着抑制人宫颈癌细胞系 JTC-26 的生长。