Benzyl-chlor-ethyl-methylsilan | 51657-50-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl-chlor-ethyl-methylsilan
• 英文别名: Benzyl-chloro-ethyl-methylsilane
• CAS: 51657-50-2
• 化学式: C₁₀H₁₅ClSi
• 分子量: 198.768
• InChiKey: PVMPLCBJGFSFSH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2931900090

反应信息

• 作为反应物：
  描述：

  Benzyl-chlor-ethyl-methylsilan 在 氨 作用下， 以 正戊烷 为溶剂， 以73%的产率得到1,3-Dibenzyl-1,3-diethyl-1,3-dimethyldisilazan
  参考文献：
  名称：

  Sila-Riechstoffe und Riechstoff-Isostere, 13. Mitt.Grimmsche Hydridisostere im Bereich der Duftstoffklasse des Linalools

  摘要：

  Substitution of the (CH3)(3)CH=CH group by (CH3)(2)C=N in linalool as well as by the (CPT3)(2)CH-CH2 group in linalool and in sila-linalool does not lead to noticeable changes of their scent qualities. On the contrary, substitution of the OH group at the tertiary C atom by NH2 or CH3 - hydride isosteric to OH according to Grimm - affords fishy or etheric instead of the original flowery smells thus indicating a transition to different basic classes of odor. Similar results were obtained with the linalool-like scents of benzyldimethylcarbinol and phenylethyldimethylcarbinol. Therefore the theory of Amoore, after which only shape and size of molecules are ruling their odor qualities, must be called in question.

  DOI：

  10.1007/bf00813801
• 作为产物：
  描述：

  甲基乙基二氯硅烷 、 氯化苄 在 magnesium 作用下， 生成 Benzyl-chlor-ethyl-methylsilan
  参考文献：
  名称：

  Wrobel, Dieter; Tacke, Reinhold; Wannagat, Ulrich, Chemische Berichte, 1982, vol. 115, # 5, p. 1694 - 1704

  摘要：

  DOI：

文献信息

• Sila-Riechstoffe und Riechstoffisostere XII . Geruchsvergleiche homologer Organoelementverbindungen der vierten Hauptgruppe (C, Si, Ge, Sn)
  作者：Ulrich Wannagat、Volker Damrath、Volker Huch、Michael Veith、Ulrich Harder

  DOI：10.1016/0022-328x(93)80293-k

  日期：1993.1

  Homologous compounds of the linalool type R(CH3)2E]-OH (with R = C6H5CH2 and C6H5CH2CH2) as well as their derivatives R(CH3)2El-OCH3 and [R(CH3)2El]2O show, in dependence of El = C, Si, Ge and Sn partly similar, but sometimes very different characteristics of odor. Unexpected are high qualities of fragrance with El = Ge, whereas derivatives with El = Sn remain scentless, obviously owing to polymerization. Noteworthy are the strong differences of odor in the system C6H5CH2El(CH3)3 from C via Si and Ge up to Sn, standing fully contrary to the postulation of Amoore whereupon smell qualities are only controlled by size and shape of molecules.C6H5CH2Sn(CH3)2OH (A1Sn) crystallizes as poly-mu-hydroxo-benzyldimethyltin with an one dimensional Sn-O-Sn-O chain (Sn-O 2.17(9) and 2.29(9) angstrom) in the monoclinic space group C2 (a = 12.696(4), b = 4.181(2), c = 10.626(3) angstrom and beta = 106.8(3)degrees).
• Einige Methoxysilane, Disiloxane und Digermoxane mit Geruchswirkung Sila-Riechstoffe. 3. Mitt.
  作者：Dieter Wrobel、Ulrich Wannagat、Ulrich Harder

  DOI：10.1007/bf00799913

  日期：1982.4
• WROBEL, D.;TACKE, R.;WANNAGAT, U.;HARDER, U., CHEM. BER., 1982, 115, N 5, 1694-1704
  作者：WROBEL, D.、TACKE, R.、WANNAGAT, U.、HARDER, U.

  DOI：——

  日期：——
• WROBEL, D.;WANNAGAT, U.;HARDER, U., MONATSH. CHEM., 1982, 113, N 4, 381-388
  作者：WROBEL, D.、WANNAGAT, U.、HARDER, U.

  DOI：——

  日期：——
• Sila-Riechstoffe und Riechstoff-Isostere, 13. Mitt.Grimmsche Hydridisostere im Bereich der Duftstoffklasse des Linalools
  作者：U. Wannagat、V. Damrath、U. Harder

  DOI：10.1007/bf00813801

  日期：1994.11

  Substitution of the (CH3)(3)CH=CH group by (CH3)(2)C=N in linalool as well as by the (CPT3)(2)CH-CH2 group in linalool and in sila-linalool does not lead to noticeable changes of their scent qualities. On the contrary, substitution of the OH group at the tertiary C atom by NH2 or CH3 - hydride isosteric to OH according to Grimm - affords fishy or etheric instead of the original flowery smells thus indicating a transition to different basic classes of odor. Similar results were obtained with the linalool-like scents of benzyldimethylcarbinol and phenylethyldimethylcarbinol. Therefore the theory of Amoore, after which only shape and size of molecules are ruling their odor qualities, must be called in question.