2-Amino-5-isopropyl-8-methyl-1-azulenecarbonitrile

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 2-Amino-5-isopropyl-8-methyl-1-azulenecarbonitrile
• 英文别名: 2-amino-8-methyl-5-propan-2-ylazulene-1-carbonitrile
• 化学式: C₁₅H₁₆N₂
• 分子量: 224.3
• InChiKey: GFDZZKWNIOIFSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Molecularly-imprinted electrochemical sensors
  申请人：Northeastern University

  公开号：US11219387B2

  公开（公告）日：2022-01-11

  Provided herein are devices (e.g., electrochemical sensors useful for detecting volatile organic compounds associated with certain diseases or conditions and/or diagnosing certain diseases or conditions). The devices comprise one or more layers of metal on a layer of silicon, and a layer of molecularly imprinted polymer in electrical communication with the one or more layers of metal, wherein the one or more layers of metal are each independently selected from a layer of chromium, platinum, gold, nickel, cobalt, tungsten, rhodium, iridium, silver, tin, titanium or tantalum, or an alloy thereof. Methods of using the devices (e.g., to detect one or more analytes in a sample, to detect and/or diagnose a disease or condition in a subject), and methods of making the devices are also provided.

  本文提供了一些装置（例如，用于检测与某些疾病或病症相关的挥发性有机化合物和/或诊断某些疾病或病症的电化学传感器）。这些装置包括硅层上的一层或多层金属，以及与一层或多层金属电通信的分子印迹聚合物层，其中一层或多层金属分别独立选自铬、铂、金、镍、钴、钨、铑、铱、银、锡、钛或钽或其合金层。此外，还提供了使用这些装置的方法（例如，检测样品中的一种或多种分析物，检测和/或诊断受试者的疾病或状况），以及制造这些装置的方法。
• Assay for vapor condensates
  申请人：Essenlix Corporation

  公开号：US11523752B2

  公开（公告）日：2022-12-13

  The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).

  本发明主要涉及提供能够简单快速地收集和分析微量蒸汽冷凝物（如呼出气体冷凝物（EBC））的方法、装置和系统。
• VOLATILE ORGANIC COMPOUNDS AS DIAGNOSTIC MARKERS FOR VARIOUS TYPES OF CANCER
  申请人：Haick Hossam

  公开号：US20120326092A1

  公开（公告）日：2012-12-27

  The present invention provides sets of VOCs for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing breast cancer, head and neck cancer, prostate cancer or colon cancer are disclosed.
• Molecularly-Imprinted Electrochemical Sensors
  申请人：Northeastern University

  公开号：US20190313944A1

  公开（公告）日：2019-10-17

  Provided herein are devices (e.g., electrochemical sensors useful for detecting volatile organic compounds associated with certain diseases or conditions and/or diagnosing certain diseases or conditions). The devices comprise one or more layers of metal on a layer of silicon, and a layer of molecularly imprinted polymer in electrical communication with the one or more layers of metal, wherein the one or more layers of metal are each independently selected from a layer of chromium, platinum, gold, nickel, cobalt, tungsten, rhodium, iridium, silver, tin, titanium or tantalum, or an alloy thereof. Methods of using the devices (e.g., to detect one or more analytes in a sample, to detect and/or diagnose a disease or condition in a subject), and methods of making the devices are also provided.
• COMPRESSED OPEN FLOW ASSAY AND USE
  申请人：Essenlix Corporation

  公开号：US20210072122A1

  公开（公告）日：2021-03-11

  The present invention relates to the methods, devices, and systems that make bio/chemical sensing (including, not limited to, immunoassay, nucleic assay, electrolyte analysis, etc.) faster, more sensitive, less steps, easy to perform, smaller amount of samples required, less or reduced (or no) needs for professional assistance, and/or lower cost, than many current sensing methods and devices. The present invention also allow a test performed by a smartphone.

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