4-[(Furan-2-ylmethyl)-amino]-quinoline-3,6-dicarboxylic acid diethyl ester

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-[(Furan-2-ylmethyl)-amino]-quinoline-3,6-dicarboxylic acid diethyl ester
• 英文别名: diethyl 4-(furan-2-ylmethylamino)quinoline-3,6-dicarboxylate
• 化学式: C₂₀H₂₀N₂O₅
• mdl: MFCD02968764
• 分子量: 368.4
• InChiKey: YLAXYEBUWDHFFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  90.7
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• 4-AMINOQUINOLINE COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS
  申请人：Olivo Paul D.

  公开号：US20090221624A1

  公开（公告）日：2009-09-03

  This invention is directed to aminoquinoline compounds, pharmaceutical compositions of such compounds, kits comprising such compounds, and uses of such compounds for preparing medicaments and treating virus-related conditions in animals.
• [EN] SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS<br/>[FR] AGONISTES ET ANTAGONISTES À PETITES MOLÉCULES DE L'ACTIVITÉ DE NR2F6 CHEZ DES NON-HUMAINS
  申请人：ZANDER THERAPEUTICS INC

  公开号：WO2019104201A1

  公开（公告）日：2019-05-31

  The present technology is directed to modulators of nuclear receptor activity, specifically to the modulation of NR2F6 activity and NR2F6 utilizing compounds, and the immune modulation and modulation of cancer stem cell activity through administration of compounds described herein. In certain embodiments the present disclosure is directed to methods of using small molecule compounds as immune modulators.
• [EN] SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY<br/>[FR] AGONISTES ET ANTAGONISTES À PETITES MOLÉCULES DE L'ACTIVITÉ DE NR2F6
  申请人：REGEN BIOPHARMA INC

  公开号：WO2019104199A1

  公开（公告）日：2019-05-31

  The present technology is directed to modulators of nuclear receptor activity, specifically to the modulation of NR2F6 activity and NR2F6 utilizing compounds, and the immune modulation and modulation of cancer stem cell activity through administration of compounds described herein. In certain embodiments the present disclosure is directed to methods of using small molecule compounds as immune modulators.