N-[(3aR,5S,6R,6aR)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]-1-phenylmethanimine oxide | 70865-99-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[(3aR,5S,6R,6aR)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]-1-phenylmethanimine oxide
• CAS: 70865-99-5
• 化学式: C₁₉H₂₅NO₆
• 分子量: 363.411
• InChiKey: RZGCDNMMNXMGGN-YJPYQABESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  74.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  N-[(3aR,5S,6R,6aR)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]hydroxylamine 、 苯甲醛 反应 12.0h， 以76%的产率得到N-[(3aR,5S,6R,6aR)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]-1-phenylmethanimine oxide
  参考文献：
  名称：

  Hydroxyamino sugar derivatives: sugar nitrones

  摘要：

  We describe in this paper the preparation of 46 new sugar nitrone derivatives and their antibacterial activity against Escherichia coli and Bacillus subtilis. (C) 1998 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0014-827x(98)00069-x

文献信息

• Hydroxyamino sugar derivatives: sugar nitrones
  作者：G Zosimo-Landolfo、J.M.J Tronchet、N Bizzozero、F Habashi、A Kamatari

  DOI：10.1016/s0014-827x(98)00069-x

  日期：1998.8

  We describe in this paper the preparation of 46 new sugar nitrone derivatives and their antibacterial activity against Escherichia coli and Bacillus subtilis. (C) 1998 Elsevier Science S.A. All rights reserved.