N-(4-fluorophenyl)-2,2,4,6-tetramethylquinoline-1(2H)-carboxamide | 352660-18-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-(4-fluorophenyl)-2,2,4,6-tetramethylquinoline-1(2H)-carboxamide
• 英文别名: N-(4-fluorophenyl)-2,2,4,6-tetramethylquinoline-1-carboxamide
• CAS: 352660-18-5
• 化学式: C₂₀H₂₁FN₂O
• 分子量: 324.4
• InChiKey: CCLDRZYJUZRKJZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• INHIBITORS OF VIRUSES
  申请人：University of Kansas

  公开号：US20180086749A1

  公开（公告）日：2018-03-29

  The present technology is directed to compounds, compositions, and methods to treat a viral infection. The compound is according to Formula I or a solvate and/or pharmaceutically acceptable salt thereof. The technology is especially suited to treat Chikungunya virus, Zika virus, Venezuelan equine encephalitis virus, and/or respiratory syncytial virus infection.