7E-Mycosinyl acetate | 17089-08-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 7E-Mycosinyl acetate
• 英文别名: [(2E)-2-hexa-2,4-diynylidene-1,6-dioxaspiro[4.4]nona-3,7-dien-9-yl] acetate
• CAS: 17089-08-6
• 化学式: C₁₅H₁₂O₄
• 分子量: 256.25
• InChiKey: XQVRVLVORPSYNU-NTUHNPAUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Extracts of Santolina chamaecyparissus
  申请人：Naturex

  公开号：EP2921053A1

  公开（公告）日：2015-09-23

  The invention relates to an extract of Santolina chamaecyparissus, to a process for preparing said extract, to a composition comprising it, and to its use a preservative, particularly as antioxidant, bactericidal and/or fungicidal.

  本发明涉及一种山苍子提取物、制备所述提取物的工艺、含有山苍子提取物的组合物，以及山苍子提取物作为防腐剂的用途，特别是作为抗氧化剂、杀菌剂和/或杀真菌剂的用途。
• Pdia4 protein as a target for diagnosis, monitoring and treatment of diabetes
  申请人：ACADEMIA SINICA

  公开号：US10987369B2

  公开（公告）日：2021-04-27

  A Pdia4 inhibitor for use in preventing, alleviating and/or treating diabetes and/or diabetes-related complications in a subject in need thereof is disclosed, wherein the Pdia4 inhibitor does not comprise cytopiloyene. A Pdia4 inhibitor and one other anti-diabetic agent for use in combination therapy in preventing, alleviating, treating diabetes and diabetes-related complications, and/or reversing diabetes in a subject in need thereof is also disclosed, wherein the Pdia4 inhibitors for use in combination therapy may comprise cytopiloyene. Also disclosed are methods for diagnosing, treating and monitoring diabetes, and methods of screening for a Pdia4 inhibitor and/or an anti-diabetic agent.

  本发明公开了一种用于预防、减轻和/或治疗糖尿病和/或糖尿病相关并发症的Pdia4抑制剂，其中Pdia4抑制剂不包含胞二磷胆碱。还公开了一种Pdia4抑制剂和一种其他抗糖尿病剂，用于联合治疗，以预防、减轻、治疗糖尿病和糖尿病相关并发症，和/或逆转需要治疗的对象的糖尿病，其中用于联合治疗的Pdia4抑制剂可包含细胞苯二氮卓。还公开了诊断、治疗和监测糖尿病的方法，以及筛选 Pdia4 抑制剂和/或抗糖尿病药物的方法。
• EXTRACTS OF SANTOLINA CHAMAECYPARISSUS
  申请人：Naturex

  公开号：EP3119206A1

  公开（公告）日：2017-01-25
• PDIA4 PROTEIN AS A TARGET FOR DIAGNOSIS, MONITORING AND TREATMENT OF DIABETES
  申请人：ACADEMIA SINICA

  公开号：US20170049794A1

  公开（公告）日：2017-02-23

  A Pdia4 inhibitor for use in preventing, alleviating and/or treating diabetes and/or diabetes-related complications in a subject in need thereof is disclosed, wherein the Pdia4 inhibitor does not comprise cytopiloyene. A Pdia4 inhibitor and one other anti-diabetic agent for use in combination therapy in preventing, alleviating, treating diabetes and diabetes-related complications, and/or reversing diabetes in a subject in need thereof is also disclosed, wherein the Pdia4 inhibitors for use in combination therapy may comprise cytopiloyene. Also disclosed are methods for diagnosing, treating and monitoring diabetes, and methods of screening for a Pdia4 inhibitor and/or an anti-diabetic agent.
• [EN] EXTRACTS OF SANTOLINA CHAMAECYPARISSUS<br/>[FR] EXTRAITS DE SANTOLINA CHAMAECYPARISSUS
  申请人：NATUREX

  公开号：WO2015140290A1

  公开（公告）日：2015-09-24

  The invention relates to an extract of Santolina chamaecyparissus, to a process for preparing said extract, to a composition comprising it, and to its use a preservative, particularly as antioxidant, bactericidal and/or fungicidal.