11,11-dimethoxy-2-undecanone | 126203-41-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 11,11-dimethoxy-2-undecanone
• 英文别名: 11,11-dimethoxyundecan-2-one
• CAS: 126203-41-6
• 化学式: C₁₃H₂₆O₃
• 分子量: 230.348
• InChiKey: DUBSFGGJXYKINU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  dec-9-ynal 在 吗啉 、 Au-TiO₂ 、 水 、 对甲苯磺酸 作用下， 以 1,4-二氧六环 、 甲醇 为溶剂， 反应 2.0h， 生成 11,11-dimethoxy-2-undecanone
  参考文献：
  名称：

  Supported Gold Nanoparticle-Catalyzed Hydration of Alkynes under Basic Conditions

  摘要：

  TiO2-supported nanosize gold particles catalyze the hydration of alkynes using morpholine as a basic cocatalyst. Unlike most homogeneous cationic gold catalysts, the TiO2-Au/morpholine system is weakly basic and is compatible with acid-sensitive functional groups (e.g., silyl ethers, ketals) or with a strongly coordinating group such as pyridine. Whats more, this gold catalyst can be recycled by simple filtration and works well in flow reactors.

  DOI：

  10.1021/ol5033859

文献信息

• Versatile Methodology to Hydrate Alkynes, in the Presence of a Wide Variety of Functional Groups, with Mercury(II) <i>p</i>-Toluensulfonamidate, Under Catalytic, Mild, and Neutral Conditions
  作者：Albert Corominas、Ángel M. Montaña

  DOI：10.1080/00397911.2012.686003

  日期：2013.8.3

  Abstract A method to generate carbonylic compounds from alkynes under mild and neutral conditions, with excellent functional group compatibility and good yields, is described. Hydration takes place under catalytic conditions by using 0.1 to 0.2 equivalents of the easily available and inexpensive mercury(II) p-toluensulfonamidate in a hydroalcoholic solution. After use, the catalyst is rendered inert

  摘要 描述了一种在温和和中性条件下由炔烃制备羰基化合物的方法，该方法具有优异的官能团相容性和良好的产率。通过在水醇溶液中使用 0.1 至 0.2 当量的易得且廉价的对甲苯磺酰胺汞 (II)，在催化条件下发生水合。使用后，催化剂变为惰性和/或循环使用。补充材料可用于本文。转至出版商的 Synthetic Communications® 在线版以查看免费的补充文件。图形概要
• Ukaji, Yutaka; Koumoto, Naosuke; Fujisawa, Tamotsu, Chemistry Letters, 1989, p. 1623 - 1626
  作者：Ukaji, Yutaka、Koumoto, Naosuke、Fujisawa, Tamotsu

  DOI：——

  日期：——
• UKAJI, YUTAKA;KOUMOTO, NAOSUKE;FUJISAWA, TAMOTSU, CHEM. LETT.,(1989) N, C. 1623-1626
  作者：UKAJI, YUTAKA、KOUMOTO, NAOSUKE、FUJISAWA, TAMOTSU

  DOI：——

  日期：——
• Supported Gold Nanoparticle-Catalyzed Hydration of Alkynes under Basic Conditions
  作者：Shengzong Liang、Jacek Jasinski、Gerald B. Hammond、Bo Xu

  DOI：10.1021/ol5033859

  日期：2015.1.2

  TiO2-supported nanosize gold particles catalyze the hydration of alkynes using morpholine as a basic cocatalyst. Unlike most homogeneous cationic gold catalysts, the TiO2-Au/morpholine system is weakly basic and is compatible with acid-sensitive functional groups (e.g., silyl ethers, ketals) or with a strongly coordinating group such as pyridine. Whats more, this gold catalyst can be recycled by simple filtration and works well in flow reactors.