1-(3-Ethoxycarbonylphenyl)-5-mercaptotetrazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(3-Ethoxycarbonylphenyl)-5-mercaptotetrazole
• 英文别名: ethyl 3-(5-sulfanylidene-2H-tetrazol-1-yl)benzoate
• 化学式: C₁₀H₁₀N₄O₂S
• 分子量: 250.28
• InChiKey: FMJRCCSOOOSPES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  98.4
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-羟基-N-(2-十四烷氧基苯)-2-萘磺酰胺 、 二氯化硫 、 1-(3-Ethoxycarbonylphenyl)-5-mercaptotetrazole 、 磺酰氯 在 二氯甲烷 、 碳酸氢钠 、 甲醇 作用下， 以 二氯甲烷 为溶剂， 反应 5.0h， 以to obtain 26.9 g of 2-(2-tetradecyloxyphenyl)carbamoyl-4-[1-(3-ethoxycarbonylphenyl)-5-tetrazolylthio]-1-naphthol的产率得到2-(2-Tetradecyloxyphenyl)carbamoyl-4-[1-(3-ethoxycarbonylphenyl)-5-tetrazolylthio]-1-naphthol
  参考文献：
  名称：

  Silver halide color photographic light-sensitive material

  摘要：

  一种银卤化物彩色摄影感光材料，包括支撑物上的银卤化物乳液层和下列一般式（I）所代表的化合物：##STR1##其中COUP代表能够与芳香族原始胺显影剂的氧化产物进行偶联反应的偶联剩基；TIME代表在偶联反应中释放并随后释放##STR2##的定时组；Z代表由一个氮原子和一个碳原子组成的单环或缩合杂环；L代表二价连结基；R.sup.1代表氢原子或烷氧羰基基团；R.sup.2代表氢原子、烷基、芳基、杂环基、酰基、磺酰基、烷氧羰基基团、氨基甲酰基基团、磺酰胺基基团、硫代酰基或硫代氨基甲酰基基团；R.sup.3代表氢原子；R.sup.2和R.sup.3可以结合形成肼酮结构；L和R.sup.1的一部分可以结合形成肼酮结构；n代表0或1。含有能够像图像地释放由一般式（I）所代表的雾化剂的化合物的银卤化物彩色摄影感光材料在保存期间具有较高的稳定性、对比度和灵敏度。还公开了使用该银卤化物彩色摄影感光材料形成彩色图像的方法。

  公开号：

  US04628024A1
• 作为试剂：
  描述：

  3-乙氧基羰基苯异硫氰酸酯 、 叠氮化钠 在 盐酸 、 1-(3-Ethoxycarbonylphenyl)-5-mercaptotetrazole 、 sodium hydroxide 、 水 、 甲醇 作用下， 以 水 为溶剂， 反应 2.5h， 以to provide 32 g of 1-(3-carboxyphenyl)-5-mercaptotetrazole的产率得到3-(5-sulfanylidene-2H-tetrazol-1-yl)benzoic acid
  参考文献：
  名称：

  Silver halide photographic materials

  摘要：

  一种银卤片光敏材料，包括至少一层银卤乳剂层的支撑，该银卤乳剂层包含基本表面潜影像型银卤晶粒，该乳剂层或至少一个与其相邻的亲水胶体层包含由通式（III）表示的化合物：##STR1## 其中L.sub.2表示--CONR--，--SO.sub.2 NR--或--NRCONR'，Z，L.sub.1，m，Ro，R.sub.1和M如本文所述。该银卤片光敏材料能够产生高对比度的负像，高灵敏度的负像和良好的点阵图像。

  公开号：

  US04737452A1

文献信息

• Silver halide color light sensitive material
  申请人：Fuji Photo Film Co., Ltd.

  公开号：US04734357A1

  公开（公告）日：1988-03-29

  A silver halide color light-sensitive material is described, which is increased in sensitivity, is adapted to form an image of high contrast, or is accelerated in development by incorporating a small amount of a specific compound which imagewise releases a foggant or a development accelerator. This compound is represented by the formula: Coup-(TIME).sub.n -FA (wherein Coup represents a coupler radical capable of undergoing a coupling reaction with an oxidized product of an aromatic primary amine developing agent; TIME represents a timing group which is eliminated from Coup by the coupling reaction and, thereafter, releases FA; n is 0 or 1; and FA represents a group which is eliminated from Coup in the coupling reaction when n is 0, whereas FA is released from TIME when n is 1. The FA has adsorption properties with respect to silver halide grains and also has a substantial fogging action with respect to the silver halide grains).

  本文描述了一种银卤化物彩色感光材料，通过加入少量的特定化合物，可以增加其灵敏度、适用于高对比度的图像形成，或者加速显影过程。该化合物的化学式为：Coup-(TIME).sub.n -FA，其中Coup代表一个偶联试剂基团，能够与芳香族一级胺显影剂的氧化产物发生偶联反应；TIME代表一个计时基团，通过偶联反应从Coup中消除，并随后释放FA；n为0或1；FA代表在n为0时从Coup中消除的基团，而在n为1时从TIME中释放的基团。FA对银卤化物颗粒具有吸附特性，并且对银卤化物颗粒具有显著的起雾作用。
• Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand
  申请人：Kaarsholm Niels Christian

  公开号：US20090123563A1

  公开（公告）日：2009-05-14

  Novel preparations comprising branched ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer. The preparations have a prolonged action designed for flexible injection regimes.

  这段话的中文翻译如下：使用分支配体的新型制备物，用于R-状态胰岛素六聚体的HisB10 Zn2+位点。这些制备物具有长效作用，旨在为灵活的注射方案设计。
• Silver halide color light-sensitive material
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0118087A2

  公开（公告）日：1984-09-12

  A silver halide color light-sensitive material is described, which is increased in sensitivity, is adapted to form an image of high contrast, or is accelerated in development by incorporating a small amount of a specific compound which imagewise releases a foggant or a development accelerator. This compound is represented by the formula: Coup-(TIME)n-FA (wherein Coup represents a coupler radical capable of undergoing a coupling reaction with an oxidized product of an aromatic primary amine developing agent; TIME represents a timing group which is eliminated from Coup by the coupling reaction and, thereafter, releases FA; n is 0 or 1; and FA represents a group which is eliminated from Coup in the coupling reaction when n is 0, whereas FA is released from TIME when n is 1. The FA has adsorption properties with respect to silver halide grains and also has a substantial fogging action with respect to the silver halide grains).

  描述了一种卤化银彩色感光材料，通过加入少量特定的化合物，在图像上释放出雾剂或显影加速剂，从而提高感光度，形成高对比度的图像，或加速显影。这种化合物的化学式如下Coup-(TIME)n-FA （其中 Coup 代表能与芳香族伯胺显影剂的氧化产物发生偶联反应的偶联基；TIME 代表通过偶联反应从 Coup 中消除并随后释放出 FA 的定时基团；n 为 0 或 1；FA 代表当 n 为 0 时在偶联反应中从 Coup 中消除的基团，而当 n 为 1 时从 TIME 中释放出 FA。）
• Silver halide photographic light-sensitive material
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0147765A2

  公开（公告）日：1985-07-10

  A silver halide photographic light-sensitive material comprising a support and at least one silver halide emulsion layer wherein the silver halide photographic light-sensitive material contains at least one compound represented by the following general formula (I): wherein COUP represents a coupler residue capable of undergoing a coupling reaction with an oxidation product of an aromatic primary amine developing agent; TIME represents a timing group which is released from COUP the coupling reaction and subsequently releases represents a group capable of being released from COUP by the coupling reaction when n is 0, or a group capable of being released from TIME after TIME which has been released from COUP when n is 1, AD being adsorptive to silver halide particles; R represents an alkyl group, an aryl group or a heterocyclic group; R' and R", which may be the same or different, each represents a hydrogen atom or a substitutent; and -NHNHCOR may be directly connected to AD when AD is combined with the benzene ring to form a condensed ring system. The'silver halide photographic light-sensitive material containing the compound represented by general formula (I) is improved in stability during storage and has a high sensitivity.

  一种卤化银感光照相材料，包括一个支撑体和至少一个卤化银乳剂层，其中卤化银感光照相材料含有至少一种由下通式(I)表示的化合物： 其中 COUP 代表能与芳香族伯胺显影剂的氧化产物发生偶联反应的偶联剂残留物； TIME 代表在偶联反应中从 COUP 释放并随后释放的定时基团 R 代表烷基、芳基或杂环基；R'和 R "可以相同或不同，各自代表氢原子或取代基；当 AD 与苯环结合形成缩合环系时，-NHNHCOR 可直接与 AD 连接。 含有通式（I）所代表化合物的'卤化银感光材料'在贮存期间的稳定性得到改善，并具有高灵敏度。
• PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER
  申请人：NOVO NORDISK A/S

  公开号：EP1585541B1

  公开（公告）日：2007-11-14