6(7)-Cinnamoylperimidine | 362047-60-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 6(7)-Cinnamoylperimidine
• 英文别名: (E)-1-(1H-perimidin-6-yl)-3-phenylprop-2-en-1-one
• CAS: 362047-60-7
• 化学式: C₂₀H₁₄N₂O
• 分子量: 298.344
• InChiKey: RFPSGLGXMUTAFY-FMIVXFBMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.82
• 重原子数：
  23.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  41.46
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  6(7)-Cinnamoylperimidine 在 aluminum tri-bromide 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 0.5h， 以36%的产率得到6-hydroxy-1,3-diazapyrene
  参考文献：
  名称：

  摘要：

  The regioselectivity of the reactions of perimidine with cinnamic acids in polyphosphoric acid (PPA) depends on the P2O5 content. Procedures were developed for the synthesis of 4(9)- and 6(7)-cinnamoylperimidines. Cyclization of the latter under the action of an excess of AlBr3 was accompanied by dearylation to form 6-hydroxy-1,3-diazapyrene.

  DOI：

  10.1023/a:1016001321161
• 作为产物：
  描述：

  苯甲醛 、 6(7)-acetylperimidine 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 反应 4.0h， 以73%的产率得到6(7)-Cinnamoylperimidine
  参考文献：
  名称：

  摘要：

  The regioselectivity of the reactions of perimidine with cinnamic acids in polyphosphoric acid (PPA) depends on the P2O5 content. Procedures were developed for the synthesis of 4(9)- and 6(7)-cinnamoylperimidines. Cyclization of the latter under the action of an excess of AlBr3 was accompanied by dearylation to form 6-hydroxy-1,3-diazapyrene.

  DOI：

  10.1023/a:1016001321161

文献信息

• ——
  作者：O. P. Demidov、I. V. Borovlev、A. F. Pozharskii

  DOI：10.1023/a:1017561405687

  日期：——
• ——
  作者：I. V. Borovlev、O. P. Demidov、A. F. Pozharskii

  DOI：10.1023/a:1021209416136

  日期：——
• ——
  作者：I. V. Borovlev、O. P. Demidov、A. F. Pozharskii

  DOI：10.1023/a:1016001321161

  日期：——

  The regioselectivity of the reactions of perimidine with cinnamic acids in polyphosphoric acid (PPA) depends on the P2O5 content. Procedures were developed for the synthesis of 4(9)- and 6(7)-cinnamoylperimidines. Cyclization of the latter under the action of an excess of AlBr3 was accompanied by dearylation to form 6-hydroxy-1,3-diazapyrene.