trans-4-Methoxy-2-methyl-3-buten | 31915-76-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: trans-4-Methoxy-2-methyl-3-buten
• 英文别名: 4-Methoxy-2-methylbuten-3 (trans)；(E)-1-Methoxy-3-methyl-1-buten；trans-Methoxy-1-isopropyl-2-aethylen；trans-1-Methoxy-3-methyl-buten-(1)；1t-methoxy-3-methyl-but-1-ene；methyl (3-methyl-1-butenyl) ether；(E)-1-Methoxy-3-methyl-1-butene；(E)-1-methoxy-3-methylbut-1-ene
• CAS: 31915-76-1
• 化学式: C₆H₁₂O
• 分子量: 100.161
• InChiKey: NDACTLNPNAMFLK-SNAWJCMRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  trans-4-Methoxy-2-methyl-3-buten 在 mercury(II) diacetate 作用下， 生成 cis-1-Methoxy-3-methyl-buten-(1)
  参考文献：
  名称：

  Thermodynamics of vinyl ethers. 19. Alkyl-substituted divinyl ethers

  摘要：

  DOI：

  10.1021/jo00428a038
• 作为产物：
  描述：

  cis-1-Methoxy-3-methyl-buten-(1) 在 mercury(II) diacetate 作用下， 生成 trans-4-Methoxy-2-methyl-3-buten
  参考文献：
  名称：

  Thermodynamics of vinyl ethers. 19. Alkyl-substituted divinyl ethers

  摘要：

  DOI：

  10.1021/jo00428a038

文献信息

• HETEROARYL DIHYDROINDOLONES AS KINASE INHIBITORS
  申请人：Boral Sougato

  公开号：US20080045526A1

  公开（公告）日：2008-02-21

  The present invention provides a compound represented by the formula: wherein the variables R 1 , b, R 6 , Y, Z, X, R and a are defined in the specification. Said compound may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, wherein said disease is selected from the group consisting of cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.

  本发明提供了一种化合物，其表示为以下公式：其中变量R1、b、R6、Y、Z、X、R和a在规范中定义。所述化合物可用于治疗与未调节的酪氨酸激酶信号转导相关的疾病的方法，所述疾病选自包括癌症、血管增生性疾病、纤维化疾病、系膜细胞增生性疾病和代谢性疾病在内的一组疾病。
• Process for the production of dienes
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0272662A2

  公开（公告）日：1988-06-29

  Aldehydes can be converted to dienes by contacting the aldehydes with a zeolite or a silica molecular sieve. The zeolite or silica molecular sieves can achieve good conversion rates and selectivities for the reaction. The reaction is especially useful for the conversion of 2-methylbutyraldehyde to isoprene.

  醛类化合物可以通过与沸石或硅分子筛接触而转化为二烯。沸石或硅分子筛可以实现良好的反应转化率和选择性。该反应对于将2-甲基丁醛转化为异戊二烯特别有用。
• Cyclopentenes, process therefor and odorant compositions therewith
  申请人：Givaudan Corporation

  公开号：US03963675A1

  公开（公告）日：1976-06-15

  Cyclopentenes, some of them novel, process for making same and odorant compositions containing them.

  环戊烯，其中一些是新颖的，制备方法以及含有它们的香味组合物。
• Heteroaryl Dihydroindolones as Kinase Inhibitors
  申请人：Boral Sougato

  公开号：US20110257238A1

  公开（公告）日：2011-10-20

  The present invention provides a compound represented by the formula: wherein the variables R 1 , b, R 6 , Y, Z, X, R and a are defined in the specification. Said compound may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, wherein said disease is selected from the group consisting of cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.

  本发明提供的化合物由以下式子表示：其中变量R1、b、R6、Y、Z、X、R和a在规范中定义。所述化合物可用于治疗与未调节的酪氨酸激酶信号传导相关的疾病的方法，其中所述疾病选自癌症、血管增生性疾病、纤维性疾病、系膜细胞增生性疾病和代谢性疾病等组。
• Process for preparing isoprene
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0272663A1

  公开（公告）日：1988-06-29

  Aldehydes can be converted to dienes by contacting the aldehydes with a non-zeolitic molecular sieve. Preferably the non-zeolitic molecular sieve has, in its calcined form, an adsorption of isobutane of at least about 2 percent by weight of the non-zeolitic molecular sieve at a partial pressure of 500 torr and a temperature of 20°C. The non-zeolitic molecular sieves can achieve good conversion rates and selectivities for the reaction. The reaction is especially useful for the conversion of 2-methylbutyraldehyde to isoprene.

  通过将醛与非沸石分子筛接触，可将醛转化为二烯。 最好是非沸石分子筛在煅烧状态下，在分压为 500 托和温度为 20 摄氏度的条件下，异丁烷的吸附量至少为非沸石分子筛重量的约 2%。 非沸石分子筛可使反应达到良好的转化率和选择性。 该反应尤其适用于将 2-甲基丁醛转化为异戊二烯。