6-Chloro-3-cyclohexyl-2,4-dihydropyrido[3,2-h][1,3]benzoxazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6-Chloro-3-cyclohexyl-2,4-dihydropyrido[3,2-h][1,3]benzoxazine
• 化学式: C₁₇H₁₉ClN₂O
• 分子量: 302.8
• InChiKey: FENILMJBVROUET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  25.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Methionine Aminopeptidase Inhibitors for Treating Infectious Diseases
  申请人：Olaleye Omonike Arike

  公开号：US20150141415A1

  公开（公告）日：2015-05-21

  The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivatives thereof or a pharmaceutical salts thereof.
• Formulations of Methionine Aminopeptidase Inhibitors for Treating Infectious Diseases
  申请人：Olaleye Omonike A.

  公开号：US20170304288A1

  公开（公告）日：2017-10-26

  Provided herein are formulations and co-solvent formulations and methods for treating an infectious disease utilizing the same. The formulations and co-solvent formulations may comprise a hydroxyquinoline analog or its pharmaceutically acceptable salt, a solvent and at least two surfactants. Also provided are methods of quantitating a hydroxyquinoline analog in a sample via chromatographic/spectrometric measurements.
• [EN] METHIONINE AMINOPEPTIDASE INHIBITORS FOR TREATING INFECTIOUS DISEASES<br/>[FR] INHIBITEURS DE LA MÉTHIONINE AMINOPEPTIDASE POUR LE TRAITEMENT DE MALADIES INFECTIEUSES
  申请人：TEXAS SOUTHERN UNIVERSITY

  公开号：WO2015077057A1

  公开（公告）日：2015-05-28

  The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivatives thereof or a pharmaceutical salts thereof.