2-n-butyl-3-phenyl-2-propen-1-ol | 5665-75-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂醇
• 英文名称: 2-n-butyl-3-phenyl-2-propen-1-ol
• 英文别名: 2-Benzylidenehexan-1-ol；2-benzylidenehexan-1-ol
• CAS: 5665-75-8
• 化学式: C₁₃H₁₈O
• 分子量: 190.285
• InChiKey: GCPNXFFSMHIMGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-苯亚甲基己醛 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 4.0h， 以85%的产率得到2-n-butyl-3-phenyl-2-propen-1-ol
  参考文献：
  名称：

  Highly enantioselective bioreduction of 2-fluorocinnamyl alcohols mediated by Saccharomyces cerevisiae

  摘要：

  Biocatalytic reduction of 2-fluorocinnamyl alcohols mediated by Saccharomyces cerevisiae was investigated in phosphate buffer solutions. Product analysis clearly showed that (S)-2-fluoro-3-arylpropanols were afforded in high yields with up to 92% ee Value. (C) 2010 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2010.01.073

文献信息

• Discrete Iron Complexes for the Selective Catalytic Reduction of Aromatic, Aliphatic, and α,β-Unsaturated Aldehydes under Water-Gas Shift Conditions
  作者：Anis Tlili、Johannes Schranck、Helfried Neumann、Matthias Beller

  DOI：10.1002/chem.201203059

  日期：2012.12.7

  Iron‐catalyzed reductions: Selective iron‐catalyzed reduction of aldehydes with hydrogen generated in situ by the water–gas shift reaction is presented (see scheme). The generality and selectivity of this mild procedure are demonstrated by the efficient reduction of various aromatic, aliphatic and α,β‐unsaturated aldehydes.

  铁催化的还原：提出了通过水煤气变换反应原位产生的氢气对铁进行醛的选择性铁催化还原（参见方案）。通过温和还原各种芳族，脂肪族和α，β-不饱和醛，可以证明这种温和方法的通用性和选择性。
• Highly enantioselective bioreduction of 2-fluorocinnamyl alcohols mediated by Saccharomyces cerevisiae
  作者：Fan Luo、Ping Wang、Yuefa Gong

  DOI：10.1016/j.tetlet.2010.01.073

  日期：2010.3

  Biocatalytic reduction of 2-fluorocinnamyl alcohols mediated by Saccharomyces cerevisiae was investigated in phosphate buffer solutions. Product analysis clearly showed that (S)-2-fluoro-3-arylpropanols were afforded in high yields with up to 92% ee Value. (C) 2010 Published by Elsevier Ltd.