2-[6-Butoxy-9-fluoro-8-methyl-5-[(2-methylpropan-2-yl)oxycarbonyl]-1,2,3,3a,4,9b-hexahydropyrrolo[3,2-c]quinolin-7-yl]-2-oxoacetic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-[6-Butoxy-9-fluoro-8-methyl-5-[(2-methylpropan-2-yl)oxycarbonyl]-1,2,3,3a,4,9b-hexahydropyrrolo[3,2-c]quinolin-7-yl]-2-oxoacetic acid
• 英文别名: 2-[6-butoxy-9-fluoro-8-methyl-5-[(2-methylpropan-2-yl)oxycarbonyl]-1,2,3,3a,4,9b-hexahydropyrrolo[3,2-c]quinolin-7-yl]-2-oxoacetic acid
• 化学式: C₂₃H₃₁FN₂O₆
• 分子量: 450.5
• InChiKey: WMJVPUGTVQEKBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  32
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• [EN] TETRACYCLINE COMPOUNDS<br/>[FR] COMPOSÉS DE TÉTRACYCLINES
  申请人：TETRAPHASE PHARMACEUTICALS INC

  公开号：WO2014036502A2

  公开（公告）日：2014-03-06

  The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I), or a pharmaceutically acceptable salt thereof, and its therapeutic use.