5-[(3R)-dithiolan-3-yl]pentanamide;(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 5-[(3R)-dithiolan-3-yl]pentanamide;(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
• 化学式: C34H50FN5O6S4
• 分子量: 772.1
• InChiKey: CZALJBRTDSXXEH-CIJOVXFLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.92
• 重原子数：
  50
• 可旋转键数：
  12
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  261
• 氢给体数：
  3
• 氢受体数：
  14

文献信息

• LIPOIC ACID COMPOSITIONS USEFUL AS ANTIMICROBIAL AGENTS
  申请人：Baylor College Of Medicine

  公开号：EP2854888A1

  公开（公告）日：2015-04-08
• [EN] LIPOIC ACID COMPOSITIONS USEFUL AS ANTIMICROBIAL AGENTS<br/>[FR] COMPOSITIONS D'ACIDE LIPOÏQUE UTILISABLES COMME AGENTS ANTIMICROBIENS
  申请人：BAYLOR COLLEGE MEDICINE

  公开号：WO2013181529A1

  公开（公告）日：2013-12-05

  The present invention includes lipoic acid and derivatives thereof useful for removing microorganisms and/or biofilm-embedded microorganisms from the surface of a medical device or subject's body. The present invention further includes compositions and methods useful for coating medical devices. The present invention further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms and/or biofilm-embedded microorganisms on the surface of a medical device or subject's body.