5-chloro-1-N'-(6-chloro-2-methoxyacridin-9-yl)pentane-1,1-diamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 5-chloro-1-N'-(6-chloro-2-methoxyacridin-9-yl)pentane-1,1-diamine
• 化学式: C₁₉H₂₁Cl₂N₃O
• 分子量: 378.3
• InChiKey: XEFKLDIJVYUMAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  60.2
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• GENETICALLY MODIFIED MICROORGANISMS CAPABLE OF PRODUCING BETA-GLUCANS AND METHODS FOR PRODUCING BETA-GLUCANS
  申请人：Wintershall Holding GmbH

  公开号：EP2870239A1

  公开（公告）日：2015-05-13
• [EN] GENETICALLY MODIFIED MICROORGANISMS CAPABLE OF PRODUCING BETA-GLUCANS AND METHODS FOR PRODUCING BETA-GLUCANS<br/>[FR] MICROORGANISMES GÉNÉTIQUEMENT MODIFIÉS POUVANT PRODUIRE DES BÊTA-GLUCANES ET PROCÉDÉS POUR LA PRODUCTION DE BÊTA-GLUCANES
  申请人：WINTERSHALL HOLDING GMBH

  公开号：WO2014006088A1

  公开（公告）日：2014-01-09

  The present invention relates to genetically modified microorganisms capable of producing beta-glucans, characterized in that said genetically modified microorganism overexpresses (i) a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity, and/or (ii) a polypeptide having 1,3-β-glucan synthase-activity, compared to a corresponding non-modified control microorganism of the same strain. The present invention also relates to the use of a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity or the use of such a polypeptide for producing β-glucans. Furthermore, the present invention relates to methods for producing β-glucans comprising the introduction of a promoter upstream of a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity thereby increasing the expression of said polynucleotide, or a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity into a microorganism being able to synthesize β-glucans.