1,1,3-Trichlor-3,3-difluor-propen | 460-64-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1,3-Trichlor-3,3-difluor-propen
• 英文别名: 1,1,3-trichloro-3,3-difluoro-propene；1,1,3-Trichloro-3,3-difluoro-1-propene；1,1,3-trichloro-3,3-difluoroprop-1-ene
• CAS: 460-64-0
• 化学式: C₃HCl₃F₂
• 分子量: 181.397
• InChiKey: WGHQJJUYJNWPNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,1,3-Trichlor-3,3-difluor-propen 在 氯 作用下， 以 水 为溶剂， 生成 1,1,1,2,2,3-hexachloro-3,3-difluoro-propane
  参考文献：
  名称：

  Substitution and Addition Reactions of the Fluoroölefins. IV.¹ Reactions of Fluoride Ion with Fluoroölefins^2,3

  摘要：

  DOI：

  10.1021/ja01497a028
• 作为产物：
  描述：

  1,1,1,3-四氯-3,3-二氟丙烷 在 氢氧化钾 作用下， 生成 1,1,3-Trichlor-3,3-difluor-propen
  参考文献：
  名称：

  1, 1, 3-trichloro-3, 3-difluoropropene

  摘要：

  公开号：

  US02628988A1

文献信息

• PROCESS FOR THE PRODUCTION OF CHLORINATED AND/OR FLUORINATED PROPENES
  申请人：Tirtowidjojo Max M.

  公开号：US20110083955A1

  公开（公告）日：2011-04-14

  The present invention provides one-step processes for the production of chlorinated and/or fluorinated propenes. The processes provide good product yield with low, e.g., less than about 20%, or even less than 10%, concentrations of residues/by-products. Advantageously, the processes may be conducted at low temperatures than 500° C. so that energy savings are provided, and/or at higher pressures so that high throughputs may also be realized. The use of catalysts or initiators may provide additional enhancements to conversion rates and selectivity, as may adjustments to the molar ratio of the reactants.

  本发明提供了用于生产氯化和/或氟化丙烯的一步法工艺。这些工艺提供了良好的产品产量，残留物/副产品的浓度低，例如低于约20%，甚至低于10%。优点是，这些工艺可以在低于500°C的低温下进行，从而提供节能，并且可以在较高的压力下进行，以实现较高的产量。使用催化剂或引发剂可能会提供对转化率和选择性的额外增强，调整反应物的摩尔比也可能有所帮助。
• CONTINUOUS LOW-TEMPERATURE PROCESS TO PRODUCE TRANS-1-CHLORO-3,3,3-TRIFLUOROPROPENE
  申请人：Pokrovski Konstantin A.

  公开号：US20120059199A1

  公开（公告）日：2012-03-08

  Disclosed is process for the production of (E) 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd(E)) by conducting a continuous reaction without the use of a catalyst. Also disclosed is an integrated system for producing hydrofluoro olefins, particularly 1233zd(E). The manufacturing process includes six major unit operations: (1) a fluorination reaction of HCC-240fa (in continuous or semi-batch mode) using HF with simultaneous removal of by-product HCl and the product 1233zd(E); (2) recycle of unreacted HCC-240fa and HF together with under-fluorinated by-products back to (1); (3) separation and purification of by-product HCl; (4) separation of excess HF back to (1); (5) purification of final product, 1233zd(E); and (6) isomerization of by-product 1233zd(Z) to 1233zd(E) to maximize the process yield.

  本发明公开了一种制备(E) 1-氯-3,3,3-三氟丙烯（HCFO-1233zd（E））的方法，通过进行连续反应而无需使用催化剂。还公开了一种生产氢氟烯的集成系统，特别是1233zd（E）。制造过程包括六个主要单元操作：（1）使用HF对HCC-240fa进行氟化反应（在连续或半批处理模式下），同时除去副产物HCl和产品1233zd（E）;（2）回收未反应的HCC-240fa和HF以及低氟化副产物返回（1）;（3）副产物HCl的分离和纯化;（4）将过量的HF分离回（1）;（5）纯化最终产品1233zd（E）;（6）将副产物1233zd（Z）异构化为1233zd（E），以最大化工艺产率。
• Process for the manufacture of halogenated propanes containing
  申请人：E. I. du Pont de Nemours and Company

  公开号：US06066769A1

  公开（公告）日：2000-05-23

  A process is disclosed for producing a compound of the formula: CF.sub.3 CHXCF.sub.3-z Y.sub.2 where X and Y are independently selected from the group consisting of H and Cl, and z is 0 or 1. The process involves (1) contacting CCl.sub.3 CHXCC.sub.3-z Y.sub.z,CCl.sub.2-z .dbd.CXCC.sub.3, and/or CCl.sub.2 CX.dbd.CC.sub.3-z Y.sub.z starting material, with hydrogen fluoride at a temperature of less than 200.degree. C. to produce a fluorination product of said starting material which includes at least 90 mole percent total of C.sub.3 HXY.sub.z Cl.sub.6-z-x F.sub.x saturated compounds and C.sub.3 XY.sub.z Cl.sub.5-z-y F.sub.y olefinic compounds, wherein x is an integer from 1 to 6-z and y is an integer from 1 to 5-z, (the fluorination product including no more than about 40 mole percent of the desired product, CF.sub.3 CHXCF.sub.3-z Y.sub.z); (2) contacting saturated compounds and olefinic compounds produced in (1) with hydrogen fluoride in the vapor phase at a temperature of from 200.degree. C. to about 400.degree. C. in the presence of a fluorination catalyst; and (3) reacting a sufficient amount of said compounds, wherein x is an integer from 1 to 5-z and olefinic compounds produced in (1) with hydrogen fluoride in the vapor phase at a temperature of from 200.degree. C. to about 400.degree. C. in the presence of a vapor phase fluorination catalyst to provide an overall selectivity to CF.sub.3 CHXCF.sub.3-z Y.sub.z of at least about 90 percent based upon the amount of starting material reacted with HF in (1) and (2).

  本发明公开了一种生产化合物的方法，该化合物的化学式为：CF.sub.3 CHXCF.sub.3-z Y.sub.2，其中X和Y是独立选择自H和Cl的一组，z为0或1。该方法包括：（1）将CCl.sub.3 CHXCC.sub.3-z Y.sub.z、CCl.sub.2-z .dbd.CXCC.sub.3和/或CCl.sub.2 CX.dbd.CC.sub.3-z Y.sub.z起始物料与氢氟酸接触，温度低于200°C，以产生起始物料的氟化产物，其中至少包括90摩尔％的C.sub.3 HXY.sub.z Cl.sub.6-z-x F.sub.x饱和化合物和C.sub.3 XY.sub.z Cl.sub.5-z-y F.sub.y烯烃化合物，其中x为1至6-z的整数，y为1至5-z的整数，（所述氟化产物中所含期望产物CF.sub.3 CHXCF.sub.3-z Y.sub.z的摩尔百分含量不超过40％）；（2）在存在氟化催化剂的条件下，将(1)中产生的饱和化合物和烯烃化合物与氢氟酸在200°C至约400°C的蒸汽相中接触；以及（3）在存在蒸汽相氟化催化剂的条件下，将(1)中产生的x为1至5-z的整数和烯烃化合物与氢氟酸在200°C至约400°C的蒸汽相中接触，以提供对于起始物料在(1)和(2)中与HF反应的总选择性至少为90％的CF.sub.3 CHXCF.sub.3-z Y.sub.z。
• PROCESS FOR THE MANUFACTURE OF HALOGENATED PROPANES CONTAINING END-CARBON FLUORINE
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0892771A1

  公开（公告）日：1999-01-27
• US6066769A
  申请人：——

  公开号：US6066769A

  公开（公告）日：2000-05-23