1,6,7-trimethyl-3,4-dihydro-2H-quinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1,6,7-trimethyl-3,4-dihydro-2H-quinoline
• 化学式: C₁₂H₁₇N
• 分子量: 175.27
• InChiKey: PKBBAEGXEHHWJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• N-SULFONYLATED TETRAHYDROQUINOLINES AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
  申请人：Glick Gary D.

  公开号：US20140088094A1

  公开（公告）日：2014-03-27

  The invention provides tetrahydroquinoline and related compounds, pharmaceutical compositions, methods of inhibiting RORγ activity, reducing the amount of IL-17 in a subject, and treating immune disorders and inflammatory disorders using such tetrahydroquinoline and related compounds are provided.

  本发明提供四氢喹啉及相关化合物、制药组合物、抑制RORγ活性的方法、减少受试者体内IL-17的数量以及使用该四氢喹啉及相关化合物治疗免疫性疾病和炎症性疾病的方法。
• LIQUID-CRYSTAL MEDIA AND LIGHT MODULATION ELEMENT
  申请人：Merck Patent GmbH

  公开号：EP3214154A1

  公开（公告）日：2017-09-06

  The present invention relates to liquid crystalline (LC) medium, to a method of its production and to the use of such LC media in polymer network liquid crystalline (PNLC) light modulation elements operated in the reverse mode. Furthermore, the present invention relates to such light modulation elements, as such, to the use of such light modulation elements as light shutters for transparent OLED displays, and to a method of production of such light modulation elements according to the present invention.

  本发明涉及液晶（LC）介质、其生产方法以及在以反向模式运行的聚合物网络液晶（PNLC）光调制元件中使用这种液晶介质。此外，本发明还涉及此类光调制元件、将此类光调制元件用作透明有机发光二极管显示器的光快门，以及根据本发明生产此类光调制元件的方法。
• Liquid-crystal media and light modulation element
  申请人：Merck Patent GmbH

  公开号：US10358601B2

  公开（公告）日：2019-07-23

  The present invention relates to liquid crystalline (LC) medium, to a method of its production and to the use of such LC media in polymer network liquid crystalline (PNLC) light modulation elements operated in the reverse mode. Furthermore, the present invention relates to such light modulation elements, as such, to the use of such light modulation elements as light shutters for transparent OLED displays, and to a method of production of such light modulation elements according to the present invention.

  本发明涉及液晶（LC）介质、其生产方法以及在以反向模式运行的聚合物网络液晶（PNLC）光调制元件中使用这种液晶介质。此外，本发明还涉及此类光调制元件、将此类光调制元件用作透明有机发光二极管显示器的光快门，以及根据本发明生产此类光调制元件的方法。
• LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DEVICE
  申请人：Merck Patent GmbH

  公开号：EP2997109B1

  公开（公告）日：2018-03-21
• LIGHT MODULATION ELEMENT
  申请人：Merck Patent GmbH

  公开号：EP3365411B1

  公开（公告）日：2020-05-13