7-Thia-2-azatricyclo[7.3.1.05,13]trideca-1(12),2,4,9(13),10-pentaene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7-Thia-2-azatricyclo[7.3.1.05,13]trideca-1(12),2,4,9(13),10-pentaene
• 英文别名: 7-thia-2-azatricyclo[7.3.1.05,13]trideca-1(12),2,4,9(13),10-pentaene
• 化学式: C₁₁H₉NS
• 分子量: 187.26
• InChiKey: COMNOTLOBLKXPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  38.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Dihydro-6-Azaphenalene Derivatives for the Treatment of CNS, Oncological Diseases and Related Disorders
  申请人：Warner Babcock Institute for Green Chemistry, LLC

  公开号：US20140094487A1

  公开（公告）日：2014-04-03

  In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.

  在一个实施例中，本申请披露了2-aza、2-oxa和2-thia-2,3-dihydro-6-azaphenalene化合物和组合物，以及使用本文所披露的化合物和组合物治疗患有神经系统疾病的患者的方法。
• DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, ONCOLOGICAL DISEASES AND RELATED DISORDERS
  申请人：The Warner-Babcock Institute For Green Chemistry LLC

  公开号：EP2900239A1

  公开（公告）日：2015-08-05
• [EN] DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, ONCOLOGICAL DISEASES AND RELATED DISORDERS<br/>[FR] DÉRIVÉS DE DIHYDRO-6-AZAPHÉNALÈNE POUR LE TRAITEMENT DU SNC, DE MALADIES ONCOLOGIQUES ET DE TROUBLES APPARENTÉS
  申请人：WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC

  公开号：WO2014052906A1

  公开（公告）日：2014-04-03

  In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.