(2R)-2-(tert-butylamino)-1-hydroxysulfanyl-4,4-dimethylpentan-3-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R)-2-(tert-butylamino)-1-hydroxysulfanyl-4,4-dimethylpentan-3-one
• 化学式: C₁₁H₂₃NO₂S
• 分子量: 233.37
• InChiKey: QTCVCASWZYIFPZ-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Boronic and Borinic Acid Compounds as Inhibitors of Sulfenic Acid-Containing Proteins
  申请人：Benkovic Stephen

  公开号：US20140147905A1

  公开（公告）日：2014-05-29

  A boronic or borinic acid compound is used to inhibit the activity of a sulfenic acid-containing protein. Thus, a biologically-active sulfenic acid-containing protein is contacted with an activity-inhibiting effective amount of a boronic or borinic acid compound of Formula I or a salt, hydrate or solvate thereof, whose components are disclosed within, and that contact is maintained for a time sufficient to inhibit the biological activity of the protein.
• Boronic and Borinic Acid Compound as Inhibitors of Sulfenic Acid-Containing Proteins
  申请人：Benkovic Stephen

  公开号：US20150140635A1

  公开（公告）日：2015-05-21

  A boronic or borinic acid compound is used to inhibit the activity of a sulfenic acid-containing protein. Thus, a biologically-active sulfenic acid-containing protein is contacted with an activity-inhibiting effective amount of a boronic or borinic acid compound of Formula I or a salt, hydrate or solvate thereof, whose components are disclosed within, and that contact is maintained for a time sufficient to inhibit the biological activity of the protein.
• US8980544B2
  申请人：——

  公开号：US8980544B2

  公开（公告）日：2015-03-17
• US9309508B2
  申请人：——

  公开号：US9309508B2

  公开（公告）日：2016-04-12