N-(2-fluorophenyl)-2-oxo-2-quinolin-3-ylacetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-(2-fluorophenyl)-2-oxo-2-quinolin-3-ylacetamide
• 化学式: C₁₇H₁₁FN₂O₂
• 分子量: 294.28
• InChiKey: UIZFJDCBIFYILK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  59.1
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• A CFTR CORRECTOR FOR THE TREATMENT OF GENETIC DISORDERS AFFECTING STRIATED MUSCLE
  申请人：UNIVERSITA' DEGLI STUDI DI PADOVA

  公开号：US20150328217A1

  公开（公告）日：2015-11-19

  The present invention relates to the use of CFTR correctors in the treatment of genetic disorders affecting striated muscle selected from sarcoglycanopathies, Brody's disease (BD) and the recessive forms of Cathecolaminergic Polymorphic Ventricular Tachycardia (CPVT).
• CFTR CORRECTOR FOR THE TREATMENT OF GENETIC DISORDERS AFFECTING STRIATED MUSCLE
  申请人：UNIVERSITA' DEGLI STUDI DI PADOVA

  公开号：US20180221347A1

  公开（公告）日：2018-08-09

  The present invention relates to the use of CFTR correctors in the treatment of genetic disorders affecting striated muscle selected from sarcoglycanopathies, Brody's disease (BD) and the recessive forms of Cathecolaminergic Polymorphic Ventricular Tachycardia (CPVT).
• US9987256B2
  申请人：——

  公开号：US9987256B2

  公开（公告）日：2018-06-05
• [EN] A CFTR CORRECTOR FOR THE TEATMENT OF GENETIC DISORDERS AFFECTING STRIATED MUSCLE<br/>[FR] CORRECTEUR DE CFTR POUR LE TRAITEMENT DE TROUBLES GÉNÉTIQUES AFFECTANT LE MUSCLE STRIÉ
  申请人：UNIV PADOVA

  公开号：WO2014086687A1

  公开（公告）日：2014-06-12

  The present invention relates to the use of CFTR correctors in the treatment of genetic disorders affecting striated muscle selected from sarcoglycanopathies, Brody's disease (BD) and the recessive forms of Cathecolaminergic Polymorphic Ventricular Tachycardia (CPVT).