2-((3,4-Dimethoxyphenyl)carbonyl)indane-1,3-dione | 374722-15-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-((3,4-Dimethoxyphenyl)carbonyl)indane-1,3-dione
• 英文别名: 2-(3,4-dimethoxybenzoyl)indene-1,3-dione
• CAS: 374722-15-3
• 化学式: C₁₈H₁₄O₅
• 分子量: 310.306
• InChiKey: HWVAJEYGUMGBMF-UHFFFAOYSA-N

物化性质

• 沸点：
  518.4±50.0 °C(Predicted)
• 密度：
  1.311±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  69.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-((3,4-Dimethoxyphenyl)carbonyl)indane-1,3-dione 在 肼 作用下， 以 乙醇 为溶剂， 反应 6.0h， 生成 3-(3,4-dimethoxyphenyl)indeno[1,2-c]pyrazol-4(1H)-one
  参考文献：
  名称：

  Substituted thioacetamides

  摘要：

  本发明涉及替代硫代乙酰胺的化学组合物、其制备方法以及在治疗疾病中使用这些组合物的用途。

  公开号：

  US06670358B2
• 作为产物：
  描述：

  邻苯二甲酸二甲酯 、 3,4-二甲氧基苯乙酮 在 sodium methylate 作用下， 以 甲苯 为溶剂， 生成 2-((3,4-Dimethoxyphenyl)carbonyl)indane-1,3-dione
  参考文献：
  名称：

  Substituted thioacetamides

  摘要：

  本发明涉及替代硫代乙酰胺的化学组合物、其制备方法以及在治疗疾病中使用这些组合物的用途。

  公开号：

  US06670358B2

文献信息

• LUMINESCENT DIKETONATE POLYMERS
  申请人：Fraser Cassandra L.

  公开号：US20090137057A1

  公开（公告）日：2009-05-28

  The present invention provides in one aspect polymeric luminescent dye compounds having fluorescent properties, phosphorescent properties, or both fluorescent and phosphorescent properties.
• COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS
  申请人：University of Virginia Patent Foundation

  公开号：US20160041177A1

  公开（公告）日：2016-02-11

  To address the need for scaffold-based oxygen concentration monitoring, a single-component, self-referenced oxygen sensor was made into nanofibers. Electrospinning process parameters were tuned to produce a biomaterial scaffold with specific morphological features. The ratio of an oxygen sensitive phosphorescence signal to an oxygen insensitive fluorescence signal was calculated at each image pixel to determine an oxygenation value. A single component boron dye-polymer conjugate was chosen for additional investigation due to improved resistance to degradation in aqueous media compared to a dye polymer blend. Standardization curves show that in fully supplemented media, the fibers are responsive to dissolved oxygen concentrations less than 15 parts per million. Spatial and temporal ratiometric gradients were observed in vitro radiating outward from the center of a dense adherent cell grouping. Sensor activation in ischemia and cell transplant models in vivo show oxygenation decreases on the scale of minutes.
• US7955861B2
  申请人：——

  公开号：US7955861B2

  公开（公告）日：2011-06-07
• US9874566B2
  申请人：——

  公开号：US9874566B2

  公开（公告）日：2018-01-23
• [EN] LUMINESCENT DIKETONATE POLYMERS<br/>[FR] POLYMÈRES DICÉTONATE LUMINESCENTS
  申请人：UNIV VIRGINIA

  公开号：WO2011011646A1

  公开（公告）日：2011-01-27

  The present invention provides in one aspect polymeric luminescent dye compounds having fluorescent properties, phosphorescent properties, or both fluorescent and phosphorescent properties. The luminescent dye compounds and compositions can be used for oxygen sensing that can be conducted without the need for invasive techniques.