4-N,4-N-dibenzyl-2-N-butyl-1-(2-methylpropyl)-2H-imidazo[4,5-e]quinoline-2,4-diamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-N,4-N-dibenzyl-2-N-butyl-1-(2-methylpropyl)-2H-imidazo[4,5-e]quinoline-2,4-diamine
• 化学式: C₃₂H₃₉N₅
• 分子量: 493.7
• InChiKey: RPLMCLQXSMXFKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  37
• 可旋转键数：
  11
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  43.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Vaccines Including Antigen From Four Strains of Influenza Virus
  申请人：Tsai Theodore

  公开号：US20140178429A1

  公开（公告）日：2014-06-26

  Vaccines of the invention include at least four influenza virus strains. In some embodiments, the vaccines are produced in cell culture rather than in eggs. In some embodiments, the vaccines include an adjuvant. In some embodiments, the vaccines are not split or whole virion vaccines, but are live or purified glycoprotein vaccines. In some embodiments, the vaccines contain substantially the same mass of hemagglutinin (HA) for each of the influenza virus strains. In some embodiments, the four strains will include two influenza A virus strains and two influenza B virus strains (‘A-A-B-B’). In other embodiments, the four strains will include three influenza A virus strains and one influenza B virus strain (‘A-A-A-B’).