3-(2-aminoethyl)-1H-indol-5-ol;benzyl N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]methyl]carbamate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-(2-aminoethyl)-1H-indol-5-ol;benzyl N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]methyl]carbamate
• 化学式: C35H41N5O3
• 分子量: 579.7
• InChiKey: JVJHWKPUWBAWIK-BHWXUOIUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.44
• 重原子数：
  43
• 可旋转键数：
  7
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.34
• 拓扑面积：
  109
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• DIFFERENTIATED CELL POPULATION OF ENDOTHELIAL CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS, COMPOSITION, SYSTEM, KIT AND USES THEREOF
  申请人：CNC - Centro de Neurociências E Biologia Molecular - Universidade de Coimbra

  公开号：EP2935567A2

  公开（公告）日：2015-10-28
• [EN] DIFFERENTIATED CELL POPULATION OF ENDOTHELIAL CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS, COMPOSITION, SYSTEM, KIT AND USES THEREOF<br/>[FR] POPULATION CELLULAIRE DIFFÉRENCIÉE DE CELLULES ENDOTHÉLIALES DÉRIVÉES DE CELLULES SOUCHES PLURIPOTENTES HUMAINES, COMPOSITION, SYSTÈME, KIT ET UTILISATIONS ASSOCIÉS
  申请人：CNC CT DE NEUROCI NCIAS E BIOLOG MOLECULAR UNIVERSIDADE DE COIMBRA

  公开号：WO2014097192A2

  公开（公告）日：2014-06-26

  The present disclosure relates to a differentiated cell population of endothelial cells derived from human pluripotent stem cells. The present invention also relates to a composition, a system and a kit comprising those cells and uses thereof. The present disclosure also described the combination of arterial ECs derived from human pluripotent stem cells with a microfluidic system to create a vascular kit for high-throughput drug screening and/or toxicology analysis. This technology may find particular use for the identification of drugs that may have a fetal cytotoxic effect.