2-Ethenyl-4-hydroxy-3-methoxy-4-(2-methylprop-2-enyl)cyclobut-2-en-1-one | 250386-41-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Ethenyl-4-hydroxy-3-methoxy-4-(2-methylprop-2-enyl)cyclobut-2-en-1-one
• CAS: 250386-41-5
• 化学式: C₁₁H₁₄O₃
• 分子量: 194.23
• InChiKey: NWZOGRRLPDPAQB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-Ethenyl-4-hydroxy-3-methoxy-4-(2-methylprop-2-enyl)cyclobut-2-en-1-one 在 三乙胺 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 生成
  参考文献：
  名称：

  Rearrangements of Linear Triquinanes to the Angular Isomers

  摘要：

  Warming substituted linear triquinanes in t-BuOK/t-BuOH resulted in their isomerization to the corresponding angularly fused isomers in good yield (59-84%). An alternate route employs a base-catalyzed intramolecular Michael addition of bicyclo[6.3.0]undecenediones, a class of compounds found to be readily-available from 1-alkenylbicyclo[3.2.0]hepten-7-ones via a "one-pot" sequence of reactions. This method is complementary to the isomerization reaction since it provides access to angular triquinanes not readily available from their linear isomers.

  DOI：

  10.1021/jo9907686
• 作为产物：
  描述：

  3-乙烯基-4-甲氧基环丁-3-烯-1,2-二酮 、 3-氯-2-甲基丙烯 在 magnesium 、 盐酸 作用下， 以 乙醚 、 四氢呋喃 为溶剂， 生成 2-Ethenyl-4-hydroxy-3-methoxy-4-(2-methylprop-2-enyl)cyclobut-2-en-1-one
  参考文献：
  名称：

  Rearrangements of Linear Triquinanes to the Angular Isomers

  摘要：

  Warming substituted linear triquinanes in t-BuOK/t-BuOH resulted in their isomerization to the corresponding angularly fused isomers in good yield (59-84%). An alternate route employs a base-catalyzed intramolecular Michael addition of bicyclo[6.3.0]undecenediones, a class of compounds found to be readily-available from 1-alkenylbicyclo[3.2.0]hepten-7-ones via a "one-pot" sequence of reactions. This method is complementary to the isomerization reaction since it provides access to angular triquinanes not readily available from their linear isomers.

  DOI：

  10.1021/jo9907686

文献信息

• Rearrangements of Linear Triquinanes to the Angular Isomers
  作者：James M. MacDougall、Harold W. Moore

  DOI：10.1021/jo9907686

  日期：1999.10.1

  Warming substituted linear triquinanes in t-BuOK/t-BuOH resulted in their isomerization to the corresponding angularly fused isomers in good yield (59-84%). An alternate route employs a base-catalyzed intramolecular Michael addition of bicyclo[6.3.0]undecenediones, a class of compounds found to be readily-available from 1-alkenylbicyclo[3.2.0]hepten-7-ones via a "one-pot" sequence of reactions. This method is complementary to the isomerization reaction since it provides access to angular triquinanes not readily available from their linear isomers.