(E)-3-(3-bromophenyl)-N-(4-piperidin-1-ylsulfonylphenyl)prop-2-enamide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-3-(3-bromophenyl)-N-(4-piperidin-1-ylsulfonylphenyl)prop-2-enamide
• 化学式: C₂₀H₂₁BrN₂O₃S
• 分子量: 449.4
• InChiKey: RUJOCNXNVJDQIK-KPKJPENVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  74.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Compounds affecting pigment production and methods for treatment of bacterial diseases
  申请人：Versitech Limited

  公开号：US11040949B2

  公开（公告）日：2021-06-22

  Provided herein are compounds, derivatives thereof, composition comprising one or more of said compounds and derivatives, and methods for prevention and/or treatment of microbial infections and/or related diseases or conditions. The present compounds and/or derivatives thereof can be represented by Formula (II): The present methods include administering to a subject an effective amount of one or more compounds of Formula (II). In one embodiment, said microbial infections are bacterial infections. More specifically, said bacterial infections are staphylococcal infections.

  本文提供了化合物、其衍生物、包含一种或多种所述化合物和衍生物的组合物，以及预防和/或治疗微生物感染和/或相关疾病或病症的方法。本化合物和/或其衍生物可由式 (II) 表示： 本方法包括向受试者施用有效量的一种或多种式（II）化合物。在一个实施方案中，所述微生物感染是细菌感染。更具体地说，所述细菌感染是葡萄球菌感染。
• COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES
  申请人：The University of Hong Kong

  公开号：US20190022038A1

  公开（公告）日：2019-01-24

  Provided herein are compounds, derivatives thereof, composition comprising one or more of said compounds and derivatives, and methods for prevention and/or treatment of microbial infections and/or related diseases or conditions. The present compounds and/or derivatives thereof can be represented by Formula (II): The present methods include administering to a subject an effective amount of one or more compounds of Formula (II). In one embodiment, said microbial infections are bacterial infections. More specifically, said bacterial infections are staphylococcal infections.