6-(3-propan-2-yl-3-azabicyclo[3.1.0]hexan-1-yl)-1H-quinolin-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6-(3-propan-2-yl-3-azabicyclo[3.1.0]hexan-1-yl)-1H-quinolin-2-one
• 化学式: C₁₇H₂₀N₂O
• 分子量: 268.35
• InChiKey: KXUAHWVTRFSPGX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Methods For Inhibiting Native And Promiscuous Uptake Of Monoamine Neurotransmitters
  申请人：McKinney Anthony

  公开号：US20140228421A1

  公开（公告）日：2014-08-14

  The present invention relates to methods of inhibiting native and promiscuous uptake of biogenic amine neurotransmitters with triple reuptake inhibitors in the treatment of conditions affected by monoamine neurotransmitters.
• METHODS FOR INHIBITING NATIVE AND PROMISCUOUS UPTAKE OF MONOAMINE NEUROTRANSMITTERS
  申请人：McKinney Anthony

  公开号：US20160199347A1

  公开（公告）日：2016-07-14

  The present invention relates to methods of inhibiting native and promiscuous uptake of biogenic amine neurotransmitters with triple reuptake inhibitors in the treatment of conditions affected by monoamine neurotransmitters.
• METHODS FOR INHIBITING NATIVE AND PROMISCUOUS UPTAKE OF MONOAMINE NEUROTRANSMISTTERS
  申请人：McKinney Anthony

  公开号：US20210047268A1

  公开（公告）日：2021-02-18

  The present invention relates to methods of inhibiting native and promiscuous uptake of biogenic amine neurotransmitters with triple reuptake inhibitors in the treatment of conditions affected by monoamine neurotransmitters.