(methoxy-ethoxy)-methyl chloride | 85232-18-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (methoxy-ethoxy)-methyl chloride
• 英文别名: methoxyethyl chloromethyl ether；1-methoxyethoxymethyl chloride；1-(Chloromethoxy)-1-methoxyethane
• CAS: 85232-18-4
• 化学式: C₄H₉ClO₂
• mdl: MFCD19233053
• 分子量: 124.567
• InChiKey: HPJVDVDJVWIFSO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-乙基-6-甲基-2-氯乙酰苯胺 、 (methoxy-ethoxy)-methyl chloride 在 PEG-400 sodium hydroxide 作用下， 以 苯 为溶剂， 反应 2.0h， 生成 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxyethoxymethyl)acetamide
  参考文献：
  名称：

  Preparation of Alkoxymethyl and Alkoxyethoxymethyl Derivatives of Acylanilines using Polyethylene Glycols as Phase Transfer Catalysts

  摘要：

  DOI：

  10.1055/s-1982-30008
• 作为产物：
  描述：

  聚合甲醛 、 1-methoxyethanol 在 盐酸 作用下， 反应 3.25h， 生成 (methoxy-ethoxy)-methyl chloride
  参考文献：
  名称：

  Preparation of Alkoxymethyl and Alkoxyethoxymethyl Derivatives of Acylanilines using Polyethylene Glycols as Phase Transfer Catalysts

  摘要：

  DOI：

  10.1055/s-1982-30008

文献信息

• Fungicidal pyridyl amides
  申请人：ICI Americas Inc.

  公开号：US04992503A1

  公开（公告）日：1991-02-12

  Novel fungicidal pyridyl amides carboxamides having the general structural formula ##STR1## wherein R is selected from the group consisting of C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkyl, benzyl, substituted benzyl wherein the substitutions are selected from the group of C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkanoyl, halogen, --NO.sub.3 and C.tbd.N, C.sub.2 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.8 alkenyl and alkanoyl; R.sub.1 is selected from the group consisting of halogen such as chlorine, fluorine and bromine, C.sub.1 -C.sub.3 alkoxy such as propoxyethoxy and methoxy, preferably methoxy and C.sub.1 -C.sub.3 haloalkoxy; R.sub.2 is selected from the group consisting of cyclopropyl, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, C.sub.2 -C.sub.6 alkoxyalkoxy, C.sub.1 -C.sub.6 alkylthio, benzyl, substituted benzyl wherein the substitutions are selected from the group of C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkanoyl, halogen, --NO.sub.3 and C.tbd.N, and arylalkylthio; and X is --O or --S; and fungicidally acceptable organic and inorganic salts thereof which are highly effective fungicides for use both as preventive and curative fungicides are disclosed herein.

  本发明涉及一种新型杀菌剂，具有一般结构式##STR1##其中R选择自C.sub.3-C.sub.6环烷基，C.sub.1-C.sub.4烷基，苯甲基，取代苯甲基，其中取代基选择自C.sub.1-C.sub.4烷基，C.sub.1-C.sub.4烷氧基，C.sub.1-C.sub.4酰基，卤素，--NO.sub.3和C.tbd.N，C.sub.2-C.sub.10烷氧基烷基，C.sub.1-C.sub.4卤代烷基，C.sub.2-C.sub.8烯基和烷酰基；R.sub.1选择自卤素，例如氯，氟和溴，C.sub.1-C.sub.3烷氧基，例如丙氧乙氧和甲氧基，优选为甲氧基和C.sub.1-C.sub.3卤代烷氧基；R.sub.2选择自环丙基，C.sub.1-C.sub.6烷基，C.sub.1-C.sub.6烷氧基，C.sub.2-C.sub.6烷氧基烷氧基，C.sub.1-C.sub.6烷硫基，苯甲基，取代苯甲基，其中取代基选择自C.sub.1-C.sub.4烷基，C.sub.1-C.sub.4烷氧基，C.sub.1-C.sub.4酰基，卤素，--NO.sub.3和C.tbd.N，和芳基烷硫基；X为--O或--S；以及其可接受的有机和无机盐，这些盐是高效的杀菌剂，可用作预防和治疗杀菌剂。
• ZUPANCIC, B. G.;SOPCIC, M., SYNTHESIS, BRD, 1982, N 11, 942-944
  作者：ZUPANCIC, B. G.、SOPCIC, M.

  DOI：——

  日期：——
• Preparation of Alkoxymethyl and Alkoxyethoxymethyl Derivatives of Acylanilines using Polyethylene Glycols as Phase Transfer Catalysts
  作者：Boris Zupančič、Mirko Sopčič

  DOI：10.1055/s-1982-30008

  日期：——