(Z)-3-(2-methoxy-5-methylphenyl)-4-methylhept-2-enoic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (Z)-3-(2-methoxy-5-methylphenyl)-4-methylhept-2-enoic acid
• 化学式: C₁₆H₂₂O₃
• 分子量: 262.34
• InChiKey: XNKCGWOOUOIZBP-RAXLEYEMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Methods of treating Parkinson's disease
  申请人：University of Macau

  公开号：US10011555B2

  公开（公告）日：2018-07-03

  This invention is directed to novel compounds isolated or derived from Alpiniae oxyphyllae fructus, chemically synthesized novel compounds, methods of preparing the novel compounds and uses thereof as neuroprotectants or drugs for treating neurodegenerative diseases such as Parkinson's disease.

  本发明涉及从Alpiniae oxyphyllae fructus中分离或衍生的新型化合物、化学合成的新型化合物、制备新型化合物的方法及其作为神经保护剂或治疗神经退行性疾病（如帕金森病）的药物的用途。
• NOVEL ANTI-NEURODEGENERATIVE NATURAL COMPOUNDS ISOLATED FROM ALPINIAE OXYPHYLLAE FRUCTUS AND TOTAL SYNTHESIS THEIROF
  申请人：University of Macau

  公开号：EP2970090A2

  公开（公告）日：2016-01-20
• NOVEL ANTI-NEURODEGENERATIVE NATURAL COMPOUNDS ISOLATED FROM ALPINIAE OXYPHYLLAE FRUCTUS AND TOTAL SYNTHESIS THEREOF
  申请人：University of Macau

  公开号：EP2970090B1

  公开（公告）日：2019-05-08
• US20140275236A1
  申请人：——

  公开号：US20140275236A1

  公开（公告）日：2014-09-18
• Novel anti-neurodegenerative natural compounds isolated from Alpiniae Oxyphyllae Fructus and their total synthesis
  申请人：University of Macau

  公开号：US20160376216A1

  公开（公告）日：2016-12-29

  This invention is directed to novel compounds isolated or derived from Alpiniae oxyphyllae fructus, chemically synthesized novel compounds, methods of preparing the novel compounds and uses thereof as neuroprotectants or drugs for treating neurodegenerative diseases such as Parkinson's disease.