4-Amino-5-(4,4-dimethylcyclohexyl)oxy-2-methylquinoline-3-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-Amino-5-(4,4-dimethylcyclohexyl)oxy-2-methylquinoline-3-carboxylic acid
• 英文别名: 4-amino-5-(4,4-dimethylcyclohexyl)oxy-2-methylquinoline-3-carboxylic acid
• 化学式: C₁₉H₂₄N₂O₃
• 分子量: 328.411
• InChiKey: ZQCLSFPVDAPUCM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  85.4
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] SUBSTITUTED 4-AMINO-5-(CYCLOHEXYLOXY)QUINOLINE-3-CARBOXYLIC ACIDS AS SWEET FLAVOR MODIFIERS<br/>[FR] ACIDES 4-AMINO-5-(CYCLOHEXYLOXY)QUINOLINE-3-CARBOXYLIQUES SUBSTITUÉS EN TANT QUE MODIFICATEURS D'ARÔME ÉDULCORANTS
  申请人：SENOMYX INC

  公开号：WO2016073251A1

  公开（公告）日：2016-05-12

  Disclosed herein are 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acid compounds having useful as sweet flavor modifiers. Also disclosed herein are ingestible compositions that include one or more of these compounds in combination with a natural or artificial sweetener.

  本文披露了具有作为甜味调味剂有用的4-氨基-5-(环己氧基)喹啉-3-羧酸化合物。本文还披露了含有这些化合物之一或多个与天然或人工甜味剂结合的可摄入组合物。
• SUBSTITUTED 4-AMINO-5-(CYCLOHEXYLOXY)QUINOLINE-3-CARBOXYLIC ACIDS AS SWEET FLAVOR MODIFIERS
  申请人：Senomyx, Inc.

  公开号：US20160185727A1

  公开（公告）日：2016-06-30

  Disclosed herein are 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acid compounds having useful as sweet flavor modifiers. Also disclosed herein are ingestible compositions that include one or more of these compounds in combination with a natural or artificial sweetener.

  本文公开了4-氨基-5-(环己氧基)喹啉-3-羧酸化合物，其作为甜味调节剂具有有用的作用。本文还公开了包含一种或多种这些化合物与天然或人造甜味剂相结合的可食用组合物。
• Beverages containing rare sugars
  申请人：The Coca-Cola Company

  公开号：US10849339B2

  公开（公告）日：2020-12-01

  Beverages comprising rare sugars and sweetness enhancers are provided herein, wherein the sweetness enhancers are present at or below the sweetness recognition threshold concentration. Also provided are methods for improving the sweetness of a beverage comprising rare sugars by adding a sweetness enhancer in a concentration at or below its sweetness recognition threshold. Beverages comprising natural high potency sweeteners and rare sugars with sugar-like characteristics are also provided, wherein the natural high potency sweetener and rare sugars are present in particular weight ratios.

  本文提供了由稀有糖和甜味增强剂组成的饮料，其中甜味增强剂的浓度达到或低于甜味识别阈值。此外，还提供了通过添加甜味增强剂，使其浓度达到或低于甜味识别阈值，从而改善包含稀有糖类的饮料甜度的方法。还提供了包含天然高效甜味剂和具有类糖特性的稀有糖的饮料，其中天然高效甜味剂和稀有糖以特定的重量比存在。
• Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers
  申请人：Firmenich Incorporated

  公开号：US11339128B2

  公开（公告）日：2022-05-24

  Disclosed herein are 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acid compounds having useful as sweet flavor modifiers. Also disclosed herein are ingestible compositions that include one or more of these compounds in combination with a natural or artificial sweetener.

  本文公开了可用作甜味调节剂的 4-氨基-5-(环己氧基)喹啉-3-羧酸化合物。本文还公开了包括一种或多种这些化合物与天然或人工甜味剂组合的可食用组合物。
• US20140271996A1
  申请人：——

  公开号：US20140271996A1

  公开（公告）日：2014-09-18