eriodictyol 7-neohesperidoside | 13241-32-2

• 物质功能分类: 分析化学 - 标准品 - 食品和饮料标准品
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: eriodictyol 7-neohesperidoside
• 英文别名: eriodictyol 7-O-neohesperidoside；neoeriocitrin；β-Neohesperidosyl-7 tetrahydroxy-3',4',5,7 flavanon; β-Neohesperidosid-7 des Eriodictyol；3',4',5-Trihydroxy-7-neohesperidosyl-flavanon；(S)-3',4',5,7-Tetrahydroxyflavanone-7-[2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranoside]；7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5-hydroxy-2,3-dihydrochromen-4-one
• CAS: 13241-32-2
• 化学式: C₂₇H₃₂O₁₅
• 分子量: 596.542
• InChiKey: OBKKEZLIABHSGY-BEDUMGIKSA-N

物化性质

• 熔点：
  277°C
• 沸点：
  960.7±65.0 °C(Predicted)
• 密度：
  1.73±0.1 g/cm3 (20 ºC 760 Torr)
• 溶解度：
  溶于甲醇；
• LogP：
  2.130 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  42
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  245
• 氢给体数：
  9
• 氢受体数：
  15

安全信息

• WGK Germany：
  3
• 海关编码：
  29389090

制备方法与用途

生物活性 Neoeriocitrin 从百日草（Drynaria Rhizome）中分离而出，在 MC3T3-E1 细胞系中表现出对增殖和成骨分化的影响。Neoeriocitrin 还是一种有效的乙酰胆碱酯酶抑制剂。

化学性质：Neoeriocitrin 是一种白色结晶粉末，可溶于甲醇、乙醇、DMSO 等有机溶剂，并来源于柑橘。

文献信息

• METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES
  申请人：Symrise AG

  公开号：US20180216152A1

  公开（公告）日：2018-08-02

  The invention relates to a method for producing flavone glycoside dihydrochalcones, having the following steps: (a) providing a transgenic microorganism containing (i) a first nucleic acid portion (A) containing a gene which codes for a bacterial chalcone isomerase and (ii) a second nucleic acid portion (B) containing a gene which codes for a bacterial enoate reductase, (b) adding one or more flavone glycosides to the transgenic microorganism under conditions which allow the simultaneous isomerization and reduction of the flavone glycoside into the flavone glycoside dihydrochalcone, and optionally (d) isolating and purifying the final product, wherein the nucleic acid portion (A) (1) is a nucleotide sequence according to SEQ ID NO:1, in which the nucleic acid portion (A′) according to SEQ ID NO:3 has been cut out, or (2) is an amino acid sequence according to SEQ ID NO:2, in which the amino acid portion (A′) according to SEQ ID NO:4 has been cut out.