N-Acetyl-beta-D-mannosamine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-Acetyl-beta-D-mannosamine
• 英文别名: N-[2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide;hydrate
• 化学式: C8H17NO7
• 分子量: 239.22
• InChiKey: VVQPUTSNIMAJPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  120
• 氢给体数：
  6
• 氢受体数：
  7

文献信息

• Codon optimized recombinant phage and methods of using same
  申请人：Institute for Environmental Health, Inc.

  公开号：US10039795B2

  公开（公告）日：2018-08-07

  Composition and methods for the detection of one or more target microbe(s) are provided. Compositions of the disclosure include at least one recombinant phage capable of infecting a target microbe, said phage comprising at least a capsid protein sequence, a ribosome binding site, and a codon-optimized marker. Compositions of the disclosure may further include an aqueous solution that enhances the ability to detect marker expression upon phage infection of the target microbe. In some embodiments the target microbe include is Listeria.

  本发明提供了用于检测一种或多种目标微生物的组合物和方法。本公开的组合物包括至少一种能够感染目标微生物的重组噬菌体，所述噬菌体至少包括一个噬菌体蛋白序列、一个核糖体结合位点和一个密码子优化标记。本公开的组合物可进一步包括一种水溶液，该水溶液可提高噬菌体感染目标微生物后检测标记表达的能力。在某些实施方案中，目标微生物包括李斯特菌。
• Recombinant phage for listeria detection
  申请人：Institute for Environmental Health, Inc.

  公开号：US10273460B2

  公开（公告）日：2019-04-30

  Methods of detecting target bacteria are provided. In some embodiments, the methods comprise exposing a sample to a phage capable of infecting target bacteria, said phage comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments, the target bacteria comprise Listeria. In some embodiments, the target bacteria are all Listeria. Recombinant Listeria phage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.

  本文提供了检测目标细菌的方法。在某些实施方案中，这些方法包括将样品暴露于能够感染目标细菌的噬菌体，所述噬菌体包括编码标记的异源核酸序列。在一些实施方案中，目标细菌包括李斯特菌。在某些实施方案中，目标细菌都是李斯特菌。还提供了包含编码标记的异源核酸序列的重组李斯特菌噬菌体，以及这种噬菌体的有用组合和包含这种噬菌体的制造品等。
• Recombinant Phage and Bacterial Detection Methods
  申请人：Sample6 Technologies, Inc.

  公开号：US20140302487A1

  公开（公告）日：2014-10-09

  Methods of detecting target bacteria are provided. In some embodiments the methods comprise exposing the sample to a phage capable of infecting a set of target bacteria and comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments the target bacteria comprise Listeria . In some embodiments the target bacteria are all Listeria . Recombinant Listeria phage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.
• CODON-OPTIMIZED RECOMBINANT PHAGE AND METHODS OF USING SAME
  申请人：Sample6 Technologies, Inc.

  公开号：US20150344930A1

  公开（公告）日：2015-12-03

  Composition and methods for the detection of one or more target microbe(s) are provided. Compositions of the disclosure include at least one recombinant phage capable of infecting a target microbe, said phage comprising at least a capsid protein sequence, a ribosome binding site, and a codon-optimized marker. Compositions of the disclosure may further include an aqueous solution that enhances the ability to detect marker expression upon phage infection of the target microbe. In some embodiments the target microbe include is Listeria.
• METHODS OF MAKING RECOMBINANT PHAGE, COMPOSITIONS AND ARTICLES OF MANUFACTURE OF SAME FOR BACTERIAL DETECTION
  申请人：Sample6 Technologies, Inc.

  公开号：US20170044502A1

  公开（公告）日：2017-02-16

  Methods of detecting target bacteria are provided. In some embodiments, the methods comprise exposing a sample to a phage capable of infecting target bacteria, said phage comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments, the target bacteria comprise Listeria . In some embodiments, the target bacteria are all Listeria . Recombinant Listeria phage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.