4a,8a-Dihydroquinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4a,8a-Dihydroquinoline
• 英文别名: 4a,8a-dihydroquinoline
• 化学式: C₉H₉N
• 分子量: 131.17
• InChiKey: ZBZFKTNCVZLDOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS
  申请人：Janssen Pharmaceutica N.V.

  公开号：EP1966214B1

  公开（公告）日：2016-11-02
• ALPHA HELIX MIMETICS AND METHODS RELATING THERETO
  申请人：PRISM BioLab Co., Ltd.

  公开号：EP2427451B1

  公开（公告）日：2019-03-20
• ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：EP2922841B1

  公开（公告）日：2017-06-07
• NEW ABSORBER FOR ORGANIC HETEROJUNCTION SOLAR CELLS
  申请人：BASF SE

  公开号：EP3036782B1

  公开（公告）日：2019-10-09
• Polymeric Carriers for Immunohistochemistry and In Situ Hybridization
  申请人：Ventana Medical Systems, Inc.

  公开号：US20150309039A1

  公开（公告）日：2015-10-29

  Certain disclosed embodiments of the present invention concern the synthesis, derivatization, conjugation to immunoglobulins and signal amplification based on discrete, relatively short polymers having plural reactive functional groups that react with plural molecules of interest. Reactive functional groups, such as hydrazides, may be derivatized with a variety of detectable labels, particularly haptens. The remaining reactive functional groups may be conjugated directly to a specific binding molecule, such as to the oxidized carbohydrate of the Fc region of the antibody. Disclosed conjugates display large signal amplification as compared to those based on molecules derivatized with single haptens, and are useful for assay methods, particularly multiplexed assays.