6-[3-(二丁基氨基)丙基氨基]喹啉-5,8-二酮 | 35976-65-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 6-[3-(二丁基氨基)丙基氨基]喹啉-5,8-二酮
• 英文名称: 6-(3-dibutylamino-propylamino)-quinoline-5,8-dione
• 英文别名: 5,8-Quinolinedione, 6-((3-dibutylamino)propyl)amino-；6-[3-(dibutylamino)propylamino]quinoline-5,8-dione
• CAS: 35976-65-9
• 化学式: C₂₀H₂₉N₃O₂
• 分子量: 343.469
• InChiKey: DYIMWUCLECRKCE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  25
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  62.3
• 氢给体数：
  1
• 氢受体数：
  5

安全信息

• 海关编码：
  2933499090

文献信息

• CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS
  申请人：Bresnick Anne R.

  公开号：US20130090355A1

  公开（公告）日：2013-04-11

  The present invention provides methods of preventing or inhibiting tumor metastasis in a subject by administering a therapeutically effective amount of (1) a compound from a group of enumerated compounds, or a pharmaceutically acceptable salt thereof; (2) an agent that covalently modifies at least one cysteine residue of S100A4 protein; or (3) an agent that inhibits the interaction between S100A4 and myosin-IIA.
• [EN] CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS<br/>[FR] AGENTS CHIMIQUES POUR LA PRÉVENTION OU L'INHIBITION DE MÉTASTASES TUMORALES
  申请人：EINSTEIN COLL MED

  公开号：WO2011146101A1

  公开（公告）日：2011-11-24

  The present invention provides methods of preventing or inhibiting tumor metastasis in a subject by administering a therapeutically effective amount of (1) a compound from a group of enumerated compounds, or a pharmaceutically acceptable salt thereof; (2) an agent that covalently modifies at least one cysteine residue of S100A4 protein; or (3) an agent that inhibits the interaction between S100A4 and myosin-IIA.