ethyl-alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate | 491851-34-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: ethyl-alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate
• 英文别名: sinapylacetoacetate；ethyl (2E)-2-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-3-oxobutanoate
• CAS: 491851-34-4
• 化学式: C₁₅H₁₈O₆
• 分子量: 294.304
• InChiKey: WHYDZKXNYRRPJE-IZZDOVSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  乙酰乙酸乙酯 、 丁香醛 在 哌啶 作用下， 以 乙醇 为溶剂， 反应 2.0h， 生成 ethyl-alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate
  参考文献：
  名称：

  Use of derivatives of sinapinic acid and compositions comprising such derivatives

  摘要：

  本发明涉及可用作化妆品成分的物质，特别是用于皮肤美白和对抗老化皮肤的化妆品剂。本发明还涉及使用这些物质制造治疗与皮肤色素沉着相关的疾病的药物。此外，本发明还涉及特定的物质。

  公开号：

  EP1967175A1

文献信息

• Photo stable organic sunscreen compositions
  申请人：EMD CHEMICALS, INC.

  公开号：US20040247536A1

  公开（公告）日：2004-12-09

  Photostable broad-spectrum organic sunscreen compositions comprising a UV-A sunscreen, such as Avobenzone, a photostabilizer, a UV-B liquid organic sunscreen, and a solubilizer and further enhancing the photostability by encapsulation using a sol-gel process.

  具有光稳定性的广谱有机防晒霜组合物包括UV-A防晒霜，如阿伏苯宗，光稳定剂，UV-B液体有机防晒霜，溶解剂，并通过溶胶-凝胶过程进行封装以进一步增强光稳定性。
• Use of derivatives of sinapinic acid and compositions comprising such derivatives
  申请人：Cognis IP Management GmbH

  公开号：EP1967175A1

  公开（公告）日：2008-09-10

  The present invention relates to substances which can be used as cosmetic ingredients, especially for skin whitening and as cosmetic agents against signs of ageing skin. The present invention also relates to the use of such substances for the manufacture of a medicament for the treatment of disorders related to the pigmentation of the skin. The invention furthermore relates to specific substances.

  本发明涉及可用作化妆品成分的物质，特别是用于皮肤美白和对抗老化皮肤的化妆品剂。本发明还涉及使用这些物质制造治疗与皮肤色素沉着相关的疾病的药物。此外，本发明还涉及特定的物质。
• PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM
  申请人：EM Industries

  公开号：US20030108492A1

  公开（公告）日：2003-06-12

  A compound of formula I 1 wherein A is a moiety which provides UV absorbing activity to the compound of formula I that comprises 1 divalent group or 2 monovalent groups, with at least one group having carbonyl (C═O) functionality, and each R is independently linear or branched C 1 -C 8 alkyl. Sunscreen formulations which contain these compounds and methods using these compounds to prepare formulations are also provided.

  化合物I1的公式为其中A是提供UV吸收活性的组分，其包括1个二价基团或2个一价基团，至少一个基团具有羰基（C═O）功能，并且每个R都是独立的线性或支链C1-C8烷基。还提供了包含这些化合物的防晒霜配方和使用这些化合物制备配方的方法。
• Photostable organic sunscreen composition
  申请人：Chaudhuri Ratan

  公开号：US20070059258A1

  公开（公告）日：2007-03-15

  The present invention relates to a sunscreen capsule comprising i) at least one UV-A organic sunscreen and ii) at least one photostabilizer; furthermore it relates to a composition for topical application comprising these capsule and methods of production and use of these capsules and compositions.

  本发明涉及一种含有i) 至少一种UV-A有机防晒剂和ii) 至少一种光稳定剂的防晒胶囊；此外，本发明还涉及一种含有这些胶囊的局部应用组合物，以及这些胶囊和组合物的生产和使用方法。
• Use of Derivatives of Sinapinic Acid and Compositions Comprising Such Derivatives
  申请人：Markert Thomas

  公开号：US20100130605A1

  公开（公告）日：2010-05-27

  The present invention relates to substances which can be used as cosmetic ingredients, especially for skin whitening and as cosmetic agents against signs of ageing skin. The present invention also relates to the use of such substances for the manufacture of a medicament for the treatment of disorders related to the pigmentation of the skin. The invention furthermore relates to specific substances.

  本发明涉及可用作化妆品成分的物质，特别是用于皮肤美白和对抗老化皮肤的化妆品成分。本发明还涉及使用这些物质制造治疗与皮肤色素沉着相关的疾病的药物。此外，本发明还涉及特定的物质。