N-[(8-hydroxy-5-nitroquinolin-7-yl)(2-methoxyphenyl)methyl]pentanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-[(8-hydroxy-5-nitroquinolin-7-yl)(2-methoxyphenyl)methyl]pentanamide
• 英文别名: N-[(8-hydroxy-5-nitroquinolin-7-yl)-(2-methoxyphenyl)methyl]pentanamide
• 化学式: C22H23N3O5
• 分子量: 409.4
• InChiKey: AWHWKYGWHLHNDQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• GLYCOSAMINOGLYCAN INHIBITORS
  申请人：Crawford Brett E.

  公开号：US20120295890A1

  公开（公告）日：2012-11-22

  Provided herein are chondroitin sulfate inhibitors, including modulators of glycosylation, and/or sulfation of galactose or N-acetyl galactosamine glycosaminoglycans.
• [EN] METHODS OF TREATMENT USING WNT INHIBITORS<br/>[FR] PROCÉDÉS DE TRAITEMENT UTILISANT DES INHIBITEURS DE WNT
  申请人：UNIV UTAH RES FOUND

  公开号：WO2010014948A1

  公开（公告）日：2010-02-04

  Described herein are methods of treating a cancer mediated by a Wnt signaling pathway, with a variety of compounds, including Wnt inhibitor compounds. Also described are methods of identifying compounds capable of modulating a Wnt signaling pathway.
• [EN] GLYCOSAMINOGLYCAN INHIBITORS<br/>[FR] INHIBITEURS DE GLYCOSAMINOGLYCANE
  申请人：ZACHARON PHARMACEUTICALS INC

  公开号：WO2011082175A2

  公开（公告）日：2011-07-07

  Provided herein are chondroitin sulfate inhibitors, including modulators of glycosylation, and/or sulfation of galactose or N-acetyl galactosamine glycosaminoglycans.