VACCINES FOR BLOCKING TRANSMISSION OF PLASMODIUM VIVAX
申请人:Kaslow C. David
公开号:US20070110772A1
公开(公告)日:2007-05-17
The present invention relates novel methods and compositions for blocking transmission of
Plasmodium vivax
which cause malaria. In particular, Pvs25 and Pvs28 polypeptides, variants, including deglycosylated forms, and fusion proteins thereof, are disclosed which, when administered to a susceptible organism, induce an immune response against a 25 kD and 28 kD protein, respectively, on the surface of
Plasmodium vivax
zygotes and ookinetes. This immune response in the susceptible organism can block transmission of malaria.
Compounds useful for treating neurodegenerative disorders
申请人:Bronk Brian Scott
公开号:US20130060013A1
公开(公告)日:2013-03-07
The present invention provides compounds of formula I:
or a pharmaceutically acceptable salt thereof, wherein each of the variables listed above are as defined and described herein, compositions thereof, and methods of using the same.