4-(6-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-(6-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid
• 化学式: C₁₉H₁₆BrNO₂
• 分子量: 370.2
• InChiKey: AOWWBFQCNXXGFN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Arf6 inhibitors and methods of synthesis and use thereof
  申请人：Navigen, Inc.

  公开号：US10849901B2

  公开（公告）日：2020-12-01

  Disclosed herein are compounds and methods for inhibiting Arf6. Pharmaceutical compositions and methods for treating a subject with an inhibitor of Arf6 are also disclosed herein.

  本文公开了抑制 Arf6 的化合物和方法。本文还公开了用 Arf6 抑制剂治疗受试者的药物组合物和方法。
• ARF6 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF
  申请人：Navigen, Inc.

  公开号：US20170189405A1

  公开（公告）日：2017-07-06

  Disclosed herein are compounds and methods for inhibiting Arf6. Pharmaceutical compositions and methods for treating a subject with an inhibitor of Arf6 are also disclosed herein.
• [EN] ARF6 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF<br/>[FR] INHIBITEURRS D'ARF6 ET LEURS MÉTHODES DE SYNTHÈSE ET D'UTILISATION
  申请人：NAVIGEN INC

  公开号：WO2015183989A1

  公开（公告）日：2015-12-03

  Disclosed herein are compounds and methods for inhibiting Arf6. Pharmaceutical compositions and methods for treating a subject with an inhibitor of Arf6 are also disclosed herein.
• [EN] COMPOUNDS AND COMPOSITIONS FOR TREATING SWEET POTATO AGAINST SWEET POTATO PATHOGENIC VIRUSES<br/>[FR] COMPOSÉS ET COMPOSITIONS POUR LE TRAITEMENT DE PATATE DOUCE CONTRE DES VIRUS PATHOGÈNES DE PATATE DOUCE
  申请人：HELSINGIN YLIOPISTO

  公开号：WO2021209689A1

  公开（公告）日：2021-10-21

  A composition comprising a compound or a salt thereof is disclosed. A method for treating a plant curatively and/or preventively against at least one plant pathogenic virus and/or against sweet potato virus disease (SPVD), as well as uses of a or a salt thereof, or of the composition, are also disclosed.