2-[4-amino-2-(1-methoxy-2-methylpropan-2-yl)-3H-imidazo[4,5-c]quinolin-9-yl]ethanol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-[4-amino-2-(1-methoxy-2-methylpropan-2-yl)-3H-imidazo[4,5-c]quinolin-9-yl]ethanol
• 化学式: C₁₇H₂₂N₄O₂
• 分子量: 314.4
• InChiKey: DJNOLOXWZBAAMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  97
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Anti PD-L1 conjugates for treating tumors
  申请人：BIRDIE BIOPHARMACEUTICALS, INC.

  公开号：US11130812B2

  公开（公告）日：2021-09-28

  The present invention discloses anti-PD-L/PD-1 Axis antibody conjugates for targeted immunotherapy, as well as compositions comprising said conjugates. Further, the present invention discloses the use of the conjugates in the treatment of tumor/cancer.

  本发明公开了用于靶向免疫疗法的抗-PD-L/PD-1 轴抗体共轭物以及包含上述共轭物的组合物。此外，本发明还公开了共轭物在治疗肿瘤/癌症中的用途。
• Anti PD-L1 Conjugates for Treating Tumors
  申请人：BIRDIE BIOPHARMACEUTICALS, INC.

  公开号：US20170290923A1

  公开（公告）日：2017-10-12

  The present invention discloses anti-PD-L/PD-1 Axis antibody conjugates for targeted immunotherapy, as well as compositions comprising said conjugates. Further, the present invention discloses the use of the conjugates in the treatment of tumor/cancer.