3-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy-4-(2-methoxyethoxy)phenyl]-2-methyl-N-(2,2,2-trifluoroethylsulfonyl)prop-2-enamide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 3-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy-4-(2-methoxyethoxy)phenyl]-2-methyl-N-(2,2,2-trifluoroethylsulfonyl)prop-2-enamide
• 化学式: C₂₁H₁₉ClF₆N₂O₆S
• 分子量: 576.9
• InChiKey: GSOASRIQJWGOER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  37
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  13

文献信息

• Therapeutic agent for diabetes
  申请人：Abe Hidenori

  公开号：US20090270631A1

  公开（公告）日：2009-10-29

  The present invention provides an agent for the prophylaxis or treatment of diabetes, which is associated with a fewer side effects such as body weight gain, adipocyte accumulation, cardiac hypertrophy and the like, and which contains a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof.

  本发明提供了一种用于预防或治疗糖尿病的药剂，其具有较少的副作用，例如体重增加、脂肪细胞积聚、心脏肥大等，并且包含以下式子所表示的化合物：其中每个符号如规范中所定义，或其盐或前药。
• Therapeutic Agent for Diabetes
  申请人：Abe Hidenori

  公开号：US20080009530A1

  公开（公告）日：2008-01-10

  The present invention provides an agent for the prophylaxis or treatment of diabetes, which is associated with a ferwer side effects such as body weight gain, adipocyte accumulation, cardiac hypertrophy and the like, and which contains a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof.

  本发明提供一种用于预防或治疗糖尿病的药剂，其与体重增加、脂肪细胞积累、心肌肥大等副作用相关，其中包含一种由以下式表示的化合物：其中每个符号如规范中所定义，或其盐或前药。