4-Benzylbenzo[f]quinolin-4-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-Benzylbenzo[f]quinolin-4-ium
• 化学式: C20H16N+
• 分子量: 270.3
• InChiKey: CYTLIRHZWTZJIZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS
  申请人：The Regents of the University of California

  公开号：US20130121925A1

  公开（公告）日：2013-05-16

  The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.

  本发明涉及一种改进的光学方法和光学传感器装置，用于在体内和/或体外的水介质中确定多羟基取代有机分子的水平。检测范围在大约400到800纳米之间。特别地，实现了一种感应装置在哺乳动物中用于确定糖的水平。具体而言，将染料与共轭含氮杂环芳基硼酸取代的双阳离子化合物结合在糖的存在下，例如果糖或葡萄糖。香兰素是首选的芳香族共轭含氮芳基硼酸取代化合物。该方法有助于确定人体中的糖水平。