6-溴-2-(2,4-二甲氧苯基)-喹啉-4-羧酸 | 351329-40-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 6-溴-2-(2,4-二甲氧苯基)-喹啉-4-羧酸
• 英文名称: 6-Bromo-2-(2,4-dimethoxyphenyl)quinoline-4-carboxylic acid
• CAS: 351329-40-3
• 化学式: C₁₈H₁₄BrNO₄
• mdl: MFCD01812952
• 分子量: 388.2
• InChiKey: LWOVGJUFNHFSQQ-UHFFFAOYSA-N

物化性质

• 沸点：
  527.9±50.0 °C(Predicted)
• 密度：
  1.500±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  68.6
• 氢给体数：
  1
• 氢受体数：
  5

安全信息

• 危险等级：
  IRRITANT

文献信息

• ANTI-VIRAL TREATMENT AND ASSAY TO SCREENFOR ANTI-VIRAL AGENT
  申请人：Severson Bill

  公开号：US20130085133A1

  公开（公告）日：2013-04-04

  The present disclosure relates to novel compounds of formulas (1) through (19) and to a method for treating humans infected with a virus including various respiratory viruses such as members of the Paramyxoviridae family (respiratory syncytial virus (RSV), human metapneumovirus (HMPV), human parainfluenza virus (HPIV), measles virus, and mumps virus) with a compound of formulas (1) through (19). The present disclosure also relates to a cytopathic effect (CPE)-based assay that will assess virus-induced CPE for screening of compounds for treating viral diseases or inhibiting a virus.