2-methoxydodecan-1-ol | 56256-81-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-methoxydodecan-1-ol
• 英文别名: 1-Hydroxy-2-methoxydodecane
• CAS: 56256-81-6
• 化学式: C₁₃H₂₈O₂
• 分子量: 216.364
• InChiKey: VTPNJVWUCJKWTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  15
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-methoxydodecan-1-ol 、 溴乙酸 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 生成 (2-methoxy-dodecyloxy)-acetic acid
  参考文献：
  名称：

  Synthesis and surface-active properties of a series of new anionic gemini compounds

  摘要：

  The synthesis of a series of new anionic dimeric amphiphiles 1-5 is described. The CMC and both static and dynamic surface tensions have been measured using the Wilhelmy plate technique and the maximum bubble pressure method. Results are compared to those obtained with the corresponding monomeric surfactants and relevant monomeric or dimeric compounds described in the literature. The relationship between the structural features of the different compounds and their properties is discussed. In particular an increase in the length of the connecting group between the two lipophilic chains lowers the CMC of the compounds which is different from results reported in the literature for other gemini compounds. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(99)00003-1
• 作为产物：
  描述：

  1-benzyloxy-2-methoxy-dodecane 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 以96%的产率得到2-methoxydodecan-1-ol
  参考文献：
  名称：

  Synthesis and surface-active properties of a series of new anionic gemini compounds

  摘要：

  The synthesis of a series of new anionic dimeric amphiphiles 1-5 is described. The CMC and both static and dynamic surface tensions have been measured using the Wilhelmy plate technique and the maximum bubble pressure method. Results are compared to those obtained with the corresponding monomeric surfactants and relevant monomeric or dimeric compounds described in the literature. The relationship between the structural features of the different compounds and their properties is discussed. In particular an increase in the length of the connecting group between the two lipophilic chains lowers the CMC of the compounds which is different from results reported in the literature for other gemini compounds. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(99)00003-1

文献信息

• Cellulose sulfate: An efficient heterogeneous catalyst for the ring-opening of epoxides with alcohols and anilines
  作者：Pooja Chaudhary、Deepa、Dhan Raj Meena、Mohd Jubair Aalam、Geeta Devi Yadav、Surendra Singh

  DOI：10.1080/00397911.2021.1910304

  日期：2021.6.18

  acts as a heterogeneous catalyst for the ring-opening of epoxides with alcohols or anilines and the Friedel-Crafts reaction between N-benzylindole and crotonaldehyde at room temperature. Methanolysis of cyclic epoxides, styrene oxide, terminal aliphatic epoxides, and glycidyl ethers were carried out using the catalyst (0.4–6.8 mg/mmol of epoxide) and afforded the corresponding products in 53–97% isolated

  摘要 硫酸纤维素是通过将α-纤维素与浓硫酸在-10°C的乙醇中酯化而合成的。纤维素主要在纤维素的3、6和3、6位硫酸化。它在室温下用作环氧化物与醇或苯胺开环以及N-苄基吲哚和巴豆醛之间的Friedel-Crafts反应的非均相催化剂。使用催化剂（0.4–6.8 mg / mmol环氧）对环状环氧化合物，氧化苯乙烯，末端脂肪族环氧化合物和缩水甘油醚进行甲醇分解，在10分钟至24小时后，分离出的产率为53–97％，得到了相应的产物。硫酸纤维素已成功回收，并最多可重复使用3个催化循环，以使氧化苯乙烯与甲醇一起开环。
• Metallized mesoporous silicate and method of oxidation with the same
  申请人：Hagiya Koji

  公开号：US20050090688A1

  公开（公告）日：2005-04-28

  A metallized mesoporous silicate which is obtained by (i) reacting (a) either a metal peroxide obtained by the reaction of an aqueous hydrogen peroxide solution with at least one metal or metal compound selected from the group consisting of the following 1) to 4) 1) tungsten 2) molybdenum 3) vanadium 4) compounds comprising 4 a ) any of tungsten, molybdenum, and vanadium and 4 b ) at least one element selected from Groups 13 to 16 (excluding oxygen) or a solution of the metal peroxide with (b) a silicon compound in the presence of an alkylamine or a quaternary ammonium salt and separating the resultant silicate; and a process for producing the metallized mesoporous silicate. Also provided is a method of organic synthesis with the silicate.

  一种金属化介孔硅酸盐，其通过以下步骤获得：(i)在烷基胺或季铵盐存在下，将(a)氢氧化物和至少选择自以下1)至4)中的一种金属或金属化合物反应得到的金属过氧化物1)钨2)钼3)钒4)包含4a)钨、钼和钒和4b)至少选择自第13至16组(不包括氧)的元素的化合物或金属过氧化物的溶液与(b)硅化合物反应，并分离所得的硅酸盐；以及生产金属化介孔硅酸盐的方法。同时提供一种使用该硅酸盐进行有机合成的方法。
• METALLIZED MESOPOROUS SILICATE AND METHOD OF OXIDATION WITH THE SAME
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1473275A1

  公开（公告）日：2004-11-03

  A metallized mesoporous silicate which is obtained by (i) reacting (a) either a metal peroxide obtained by the reaction of an aqueous hydrogen peroxide solution with at least one metal or metal compound selected from the group consisting of the following 1) to 4) 1) tungsten 2) molybdenum 3) vanadium 4) compounds comprising 4a) any of tungsten, molybdenum, and vanadium and 4b) at least one element selected from Groups 13 to 16 (excluding oxygen) or a solution of the metal peroxide with (b) a silicon compound in the presence of an alkylamine or a quaternary ammonium salt and separating the resultant silicate; and a process for producing the metallized mesoporous silicate. Also provided is a method of organic synthesis with the silicate.

  一种金属化介孔硅酸盐，它是通过(i)使(a)过氧化氢水溶液与至少一种选自以下组别的金属或金属化合物反应而得到的过氧化金属1)至4)1)钨2)钼3)钒4)包括4a)钨、钼和钒中的任何一种和4b)至少一种选自第13至16组的元素(不包括氧)的化合物或过氧化金属的溶液与(b)硅化合物反应而得到的、钼和钒以及 4b) 至少一种选自第 13 组至第 16 组的元素（不包括氧）的化合物，或在烷基胺或季铵盐存在下，过氧化金属与 (b) 硅化合物的溶液，并分离得到的硅酸盐；以及生产金属化介孔硅酸盐的工艺。此外，还提供了一种用硅酸盐进行有机合成的方法。
• Organotin phosphate condensates as a catalyst of selective ring-opening of oxiranes by alcohols
  作者：Junzo Otera、Yoshihisa Niibo、Naofumi Tatsumi、Hitoshi Nozaki

  DOI：10.1021/jo00237a009

  日期：1988.1
• Ring opening of epoxides with alcohols using Fe(Cp)2BF4 as catalyst
  作者：Geeta Devi Yadav、Surendra Singh

  DOI：10.1016/j.tetlet.2014.05.017

  日期：2014.7

  Fe(Cp)(2)BF4 is an efficient catalyst for the alcoholysis of aromatic, aliphatic, and cyclic epoxides giving excellent yields of the corresponding beta-alkoxy alcohols under ambient conditions. The methanolysis of styrene oxide using Fe(Cp)(2)BF4 as a catalyst (5 mol %) gave excellent yield of 2-methoxy-2-phenylethanol with complete regio-selectivity. The ring opening of cyclic epoxides gave 77-97% yields of trans-beta-methoxy alcohols, in 0.5-6 h. The use of 1,2-epoxyhexane and 1,2-epoxydodecane as substrates gave both regioisomers in excellent yields. The first order rate of reaction with respect to catalyst was observed for the kinetics of ring opening of 1,2-epoxyhexane with methanol. (C) 2014 Elsevier Ltd. All rights reserved.